[HTML][HTML] Development and testing of species-specific ELISA assays to measure IFN-γ and TNF-α in bottlenose dolphins (Tursiops truncatus)

KC Eberle, SK Venn-Watson, ED Jensen, J LaBresh… - Plos one, 2018 - journals.plos.org
Monitoring the immune status of cetaceans is important for a variety of health conditions.
Assays to quantify cytokines, especially pro-inflammatory cytokines, could be employed, in …

[HTML][HTML] An update on the development of a bottlenose dolphin, Tursiops truncatus, immune reagent toolkit

RE Sacco, ED Jensen, YB Sullivan, J LaBresh… - Veterinary Immunology …, 2024 - Elsevier
There are extensive immunological reagents available for laboratory rodents and humans.
However, for veterinary species there is a need for expansion of immunological toolkits, with …

[PDF][PDF] Recent Cytokine Findings and Implications Towards Health Assessment of the Bottlenose Dolphin (Tursiops truncatus)

A Vecchione, MM Peden-Adams, TA Romano… - Aquatic …, 2008 - academia.edu
Bottlenose dolphins (Tursiops truncatus) are toplevel marine predators and represent a
sentinel species for ocean health. The study of cytokines and immunocellular function are …

Development of an interleukin-2 receptor expression assay and its use in evaluation of cellular immune responses in bottlenose dolphin (Tursiops truncatus)

KL Erickson, L DiMolfetto-Landon… - Journal of Wildlife …, 1995 - meridian.allenpress.com
We describe optimization of a peripheral blood mononuclear leukocyte proliferation assay
and development of an interleukin-2 receptor (IL-2R) expression assay for bottlenose …

[HTML][HTML] Monitoring bottlenose dolphin leukocyte cytokine mRNA responsiveness by qPCR

AR Hofstetter, KC Eberle, SK Venn-Watson… - PloS one, 2017 - journals.plos.org
Both veterinarians caring for dolphins in managed populations and researchers monitoring
wild populations use blood-based diagnostics to monitor bottlenose dolphin (Tursiops …

Cytokine analysis in Atlantic bottlenose dolphins

RE Cirocco, C Bigger, M Renart, G Bossart - … and Comparative Immunology, 1997 - infona.pl
Most components of the immune system demonstrate amino acid and nucleotide sequence
homology among higher vertebrates. Cytokines, regulatory cell signalling proteins, have …

In-vitro lymphocyte response of bottlenose dolphins (Tursiops truncatus): mitogen-induced proliferation

GP Lahvis, RS Wells, D Casper, CS Via - Marine Environmental Research, 1993 - Elsevier
Stranded bottlenose dolphins, Tursiops truncatus, exhibit infections suggestive of immune
dysfunction. Concurrent high levels of immunotoxic pollutants indicate that one possible …

Baseline circulating immunoglobulin G levels in managed collection and free-ranging bottlenose dolphins (Tursiops truncatus)

CL Ruiz, HH Nollens, S Venn-Watson, LG Green… - Developmental & …, 2009 - Elsevier
Serum immunoglobulin levels can be used as markers for immune status. However, tools to
evaluate immune function and status of cetaceans under veterinary care have been limited …

Comparative analysis of the specificity of monoclonal antibodies developed against the bottlenose dolphin, Tursiops truncatus, TNF-α, IL1-β, IL-6, IL-8, IL-10 with …

MM Elnaggar, GS Abdellrazeq, RE Sacco… - Veterinary Immunology …, 2022 - Elsevier
Opportunities to include Cetancodontamorpha in the study of the evolution of the immune
system in the clades of Artiodactylamorpha, Ruminantiamorpha, Suinamorpha, and …

[HTML][HTML] Phenotyping and comparing the immune cell populations of free-ranging Atlantic bottlenose dolphins (Tursiops truncatus) and dolphins under human care

M Nouri-Shirazi, BF Bible, M Zeng, S Tamjidi… - BMC veterinary …, 2017 - Springer
Background Studies suggest that free-ranging bottlenose dolphins exhibit a suppressed
immune system because of exposure to contaminants or microorganisms. However, due to a …