Matrine is a quinolizidine alkaloid isolated from the roots of Sophora flavescens (Kushen),
Sophora tonkinensis, and Sophora alopecuroides (Kudouzi). Matrine and its derivatives …

Cancer is the second leading cause of mortality and has resulted in about 9.6 million deaths
around the world in 2018. Cancer-caused deaths are expected to be 11.5 million by 2030 all …

Background & Objective: The emergence of multidrug-resistant virus, bacteria and fungi has
created an urgent need for the development of novel antibiotic drugs from natural products …

(+)-12α-Hydroxysophocarpine (8), a new quinolizidine alkaloid was isolated from the roots
of Sophora flavescens, together with 10 known quinolizidine alkaloids,(+)-oxymatrine (1),(+) …

A rapid, sensitive and selective high-performance liquid chromatography tandem mass
spectrometric method (HPLC-MS) has been developed and validated for the simultaneous …

Five novel quinolizidine-based alkaloids (1–5) were obtained from the seeds of Sophora
alopecuroides L. Compounds 1 and 2 are the first examples of sparteine-indolizine and …

Abstract Saposhnikovia divaricata (Turcz.) Schischk., a perennial herb belonging to the
family Umbelliferae, is widely distributed in Northeast Asia. Its dried root (Radix …

Although the quinolizidine alkaloids and flavonoids, the main active components of the
traditional Chinese medicine Sophora flavescens, have been largely investigated, a new …

Abstract Ethnopharmacological relevance Sophora japonica (Fabaceae), also known as
Huai (Chinese: 槐), is a medium-sized deciduous tree commonly found in China, Japan …

Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …