Neutrophils are associated with pro‐inflammation and contribute to pathophysiology of
ischemic stroke. Prevention of neutrophils from infiltrating into ischemic area can be a …

Ischemic stroke leads to high disability and mortality. The limited delivery efficiency of most
therapeutic substances is a major challenge for effective treatment of ischemic stroke …

High level of detrimental factors including reactive oxygen species (ROS) and inflammatory
cytokines accumulated in the infarct core and their erosion to salvageable penumbra are key …

Neuroinflammation has emerged as a major concern in ischemic stroke therapy because it
exacebates neurological dysfunction and suppresses neurological recovery after …

Stroke is a serious public health problem that raises expenses for society and causes long-
term impairment and death. However, due to restricted blood–brain barrier (BBB) …

Ischemic stroke is a dreadful vascular disorder that poses enormous threats to the public
health. Due to its complicated pathophysiological features, current treatment options after …

In acute ischemic stroke, neutrophils contribute to ischemia-reperfusion injury through
producing neutrophil extracellular traps (NETs), which promote the interaction of platelets …

Background Ischemic stroke is an acute and severe neurological disease, and reperfusion is
an effective way to reverse brain damage after stroke. However, reperfusion causes …

Ischemic stroke is an acute and severe neurological disease, resulting in disability and
death. The poor drug delivery to cerebral ischemic regions is a key challenge of ischemic …

Neutrophils are implicated in numerous inflammatory diseases, and especially in acute
ischemic stroke (AIS). The unchecked migration of neutrophils into cerebral ischemic …