Bone marrow mesenchymal stromal cells (BM-MSCs) have a critical role in tissue
regeneration and in the hematopoietic niche due to their differentiation and self-renewal …

Background MicroRNAs (miRNAs) regulate gene expression post-transcriptionally via
mRNA degradation. As a result, they have an impact on a variety of pathways in organisms …

The discovery of microRNAs (miRNAs) has opened a new avenue for both diagnosis and
treatment of cancers. Accumulating experimental evidences indicate that miRNAs are …

Differences in gene expression patterns have been documented not only in Multiple
Sclerosis patients versus healthy controls but also in the relapse of the disease. Recently a …

Neuroblastomas (NB) are childhood malignant tumors originating in the sympathetic
nervous system. MicroRNAs (miRNAs) play an essential regulatory role in tumorigenesis …

Background MicroRNAs (miRNAs) are a large group of RNAs that play important roles in
regulating gene expression and protein translation. Several studies have indicated that …

MicroRNAs (miRNAs) are noncoding small RNA molecules that act as decisive roles in cell
proliferation and differentiation processes by targeted inhibition of mature mRNA. In this …

Central nervous system (CNS) is an increasingly common site of isolated metastasis for
patients with Stage 4 neuroblastoma. To explore the microRNA (miRNA) profile of this …

MicroRNAs (MIRs) perform critical regulatory functions within cell networks, both in
physiology as well as in pathology. Through the positional gene candidate approach, we …

The proteosome inhibitor bortezomib has revolutionized the treatment of multiple
hematologic malignancies, but in many cases, its efficacy is limited by a dose-dependent …