Longitudinal observations on mutations conferring ganciclovir resistance in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis: The …

DA Jabs, BK Martin, MS Forman, JP Dunn… - American journal of …, 2001 - Elsevier
PURPOSE: Cytomegalovirus retinitis is the most common intraocular infection in patients
with acquired immunodeficiency syndrome (AIDS). With prolonged suppressive …

Oral ganciclovir for cytomegalovirus retinitis in patients with AIDS: results of two randomized studies

KE Squires - Aids, 1996 - journals.lww.com
Objective: To determine the relative effectiveness of an oral formulation compared to a
standard intravenous regimen of ganciclovir in preventing the progression of …

A case of ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with AIDS: longitudinal molecular analysis of the CMV viral load and viral mutations in blood …

G Boivin, C Gilbert, M Morissette, J Handfield… - Aids, 1997 - journals.lww.com
Objectives: To study the temporal relationships between cytomegalovirus (CMV) viral load
and specific UL97 mutations in polymorphonuclear leukocytes (PMNL) and plasma samples …

Rate of emergence of cytomegalovirus (CMV) mutations in leukocytes of patients with acquired immunodeficiency syndrome who are receiving valganciclovir as …

G Boivin, C Gilbert, A Gaudreau… - The Journal of …, 2001 - academic.oup.com
The emergence of mutations conferring ganciclovir resistance was evaluated in an open-
label randomized clinical trial that compared oral valganciclovir with intravenous ganciclovir …

Cytomegalovirus resistance to ganciclovir and clinical outcomes of patients with cytomegalovirus retinitis

DA Jabs, BK Martin, MS Forman, L Hubbard… - American journal of …, 2003 - Elsevier
PURPOSE: To evaluate whether cytomegalovirus resistant to ganciclovir, detected in either
the blood or urine, correlates with adverse ocular outcomes. DESIGN: Prospective cohort …

Mutations conferring ganciclovir resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis

DA Jabs, BK Martin, MS Forman… - The Journal of …, 2001 - academic.oup.com
Cytomegalovirus (CMV) retinitis is among the most common opportunistic infections in
patients with acquired immunodeficiency syndrome. In a prospective study of 210 patients …

Intravitreal ganciclovir concentration after intravenous administration in AIDS patients with cytomegalovirus retinitis: implications for therapy

BD Kuppermann, JI Quiceno, MF Aguilar… - Journal of Infectious …, 1993 - academic.oup.com
To determine whether therapeutic intravitreal concentrations of ganciclovirare achieved after
intravenous administration, vitreous samples were obtained intraoperatively from 23 eyes of …

Pathophysiology and treatment of clinically resistant cytomegalovirus retinitis

M Flores-Aguilar, BD Kuppermann, JI Quiceno… - Ophthalmology, 1993 - Elsevier
Purpose: To determine the incidence, pathophysiology, clinical outcome, and survival in
patients with clinically resistant retinitis. Methods: Cytomegalovirus (CIVIV) retinitis was …

Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma

HB Moss, S Chavala, E Say… - Journal of clinical …, 2012 - Am Soc Microbiol
ABSTRACT A patient with systemic cytomegalovirus (CMV), including chorioretinitis,
received localized and systemic ganciclovir, systemic cidofovir analog, and localized …

High dose oral ganciclovir treatment for cytomegalovirus retinitis

JP Lalezari, DN Friedberg, J Bissett, MF Giordano… - Journal of clinical …, 2002 - Elsevier
Background: The oral formulation of ganciclovir is approved at a dose of 3.0 g/day for
maintenance treatment of cytomegalovirus (CMV) retinitis following an initial induction …