Ganciclovir resistance and UL97 gene mutations in cytomegalovirus blood isolates from patients with AIDS treated with ganciclovir

B Abraham, S Lastere, J Reynes… - Journal of clinical …, 1999 - Elsevier
Background: Treatment of cytomegalovirus (CMV) diseases with protracted administration of
ganciclovir can promote the development of resistant CMV that is associated with a poor …

Low plasma concentrations achieved with conventional schedules of administration of ganciclovir in patients with AIDS

C Piketty, C Bardin, J Gilquin, V Mahe… - Journal of Infectious …, 1996 - academic.oup.com
Plasma concentration of ganciclovir was studied prospectively in 15 AIDS patients treated
for acute cytomegalovirus (CMV) retinitis. Ganciclovir was administered at a mean dose of …

Sensitivities of Human Cytomegalovirus (HCMV) Clinical Isolates to Cidofovir.

JM Cherrington, SJW Allen, AS Mulato, R Miner… - Antiviral Research, 1995 - elibrary.ru
Cidofovir [CDV,(S)-(1)-(3-Hydroxy-2-phosphonylmethoxypropyl) cytosine, HPMPC]
sensitivities among HCMV clinical isolates from patients enrolled in the GS-101 clinical trial …

Long-term outpatient treatment of CMV retinitis with ganciclovir in AIDS patients.

RW Weisenthal, SH Sinclair, I Frank… - British journal of …, 1989 - bjo.bmj.com
Cytomegaloviral retinitis was diagnosed in nine eyes of seven patients with acquired
immune deficiency syndrome (AIDS) on the basis of the characteristic ocular findings and a …

Spectrum and treatment of cytomegalovirus disease in persons with AIDS

SA Spector - Journal of the International Association of …, 1996 - pubmed.ncbi.nlm.nih.gov
AIDS: In persons with AIDS (PWAs), cytomegalovirus (CMV) infection can cause a broad
spectrum of clinical manifestations. The most common clinical manifestations associated …

Foscarnet and Ganciclovir in the treatment of CMV retinitis in AIDS patients: a randomised comparison

G Moyle, C Harman, S Mitchell… - Journal of …, 1992 - journalofinfection.com
Ganciclovir and Foscarnet were compared in an open randomised trial as treatment and
secondary prophylaxis of cytomegalovirus (CMV) retinitis in patients with AIDS. Patients …

In vitro susceptibility of cytomegalovirus isolates from immunocompromised patients to acyclovir and ganciclovir

NL Cole, HH Balfour Jr - Diagnostic microbiology and infectious disease, 1987 - Elsevier
Fifty-four isolates of cytomegalovirus (CMV) from 25 immunocompromised patients with
CMV infections were examined in a plaque reduction assay to determine in vitro …

Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease

S Chou, G Marousek, S Guentzel… - Journal of Infectious …, 1997 - academic.oup.com
In a human immunodeficiency virus-infected subject, cytomegalovirus (CMV) isolated 9
months after the patient began oral ganciclovir prophylaxis was resistant to ganciclovir and …

Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis

RC Walton, SM Whitcup, BU Mueller, LL Lewis… - Ophthalmology, 1995 - Elsevier
Purpose: Children with the acquired immune deficiency syndrome (AIDS) and
cytomegalovirus (CMV) retinitis may not complain of symptoms despite the presence of …

CMV Enzephalitis unter Ganciclovir Therapie einer CMV Retinitis

TF Schwarz, G Jäger, K Loeschke, I Hanus, W Feiden… - Infection, 1990 - Springer
An AIDS patient with cytomegalovirus (CMV) retinitis was treated with ganciclovir (10 mg/kg)
for four days followed by 5 mg/kg for 69 days. Clinically, CMV retinitis improved during …