An AIDS patient with cytomegalovirus (CMV) retinitis was treated with ganciclovir (10 mg/kg)
for four days followed by 5 mg/kg for 69 days. Clinically, CMV retinitis improved during …

Cytomegalovirus (CMV) resistance to ganciclovir occurs via mutations in the UL97 gene.
CMV DNA, from vitreous and blood specimens and from culture isolates from 87 patients …

Background Valganciclovir is an orally administered prodrug that is rapidly hydrolyzed to
ganciclovir. We compared the effects of oral valganciclovir with those of intravenous …

Abstract purpose: Cytomegalovirus (CMV) retinitis in patients with the acquired
immunodeficiency, syndrome (AIDS) requires lifelong therapy with either intravenous …

Rapid, quantitative, and objective determination of the susceptibilities of human
cytomegalovirus (HCMV) clinical isolates to ganciclovir has been assessed by an assay that …

Objectives: Despite life-long maintenance therapy, cytomegalovirus (CMV) retinitis
frequently progresses in patients with AIDS. Virological markers that could clarify …

Purpose To determine the efficacy of combined ganciclovir and foscarnet intravitreal
injections in controlling clinically resistant cytomegalovirus retinitis in a 3 7-year-old man …

Methods Patients diagnosed as having CMV retinitis who underwent ocular PCR analysis
for ganciclovir resistance from 2 tertiary referral institutions (National Eye Institute, National …

Abstract A phase I/II study evaluated the pharmacokinetics, tolerability, and antiviral activity
of oral ganciclovir in persons infected with human immunodeficiency virus (HIV). Oral …

• Cytomegalovirus retinopathy lesions in patients with the acquired immunodeficiency
syndrome may continue to enlarge despite ganciclovir sodium treatment. In an historical …