Role of oxidative stress and reduced endogenous hydrogen sulfide in diabetic nephropathy
A Hussain Lodhi, FD Ahmad, K Furwa… - Drug Design …, 2021 - Taylor & Francis
Purpose Persistent hyperglycemia lead towards depletion of hydrogen sulfide (H2S)
resulting in generation of oxidative stress and diabetic nephropathy. The aim of the current …
resulting in generation of oxidative stress and diabetic nephropathy. The aim of the current …
H2S donors attenuate diabetic nephropathy in rats: Modulation of oxidant status and polyol pathway
MM Safar, RM Abdelsalam - Pharmacological Reports, 2015 - Springer
Background Sulfurous mineral water and its main active ingredient sodium hydrosulfide
(NaHS) are major sources of H 2 S. The present study aimed to explore their protective effect …
(NaHS) are major sources of H 2 S. The present study aimed to explore their protective effect …
[HTML][HTML] H2S Inhibits Hyperglycemia-Induced Intrarenal Renin-Angiotensin System Activation via Attenuation of Reactive Oxygen Species Generation
Decrease in endogenous hydrogen sulfide (H2S) was reported to participate in the
pathogenesis of diabetic nephropathy (DN). This study is aimed at exploring the relationship …
pathogenesis of diabetic nephropathy (DN). This study is aimed at exploring the relationship …
[HTML][HTML] Hydrogen sulfide alleviates diabetic nephropathy in a streptozotocin-induced diabetic rat model
X Zhou, Y Feng, Z Zhan, J Chen - Journal of Biological Chemistry, 2014 - ASBMB
Accumulating evidence has demonstrated that hydrogen sulfide (H 2 S) plays critical roles in
the pathogenesis of chronic kidney diseases. This study was designed to investigate …
the pathogenesis of chronic kidney diseases. This study was designed to investigate …
[HTML][HTML] Combined effect of hydrogen sulphide donor and losartan in experimental diabetic nephropathy in rats
Background Diabetic nephropathy (DN) is one of the complex complications of Diabetes
Mellitus (DM). The present study has been designed to examine protective role of hydrogen …
Mellitus (DM). The present study has been designed to examine protective role of hydrogen …
Hydrogen sulfide treatment promotes glucose uptake by increasing insulin receptor sensitivity and ameliorates kidney lesions in type 2 diabetes
R Xue, DD Hao, JP Sun, WW Li, MM Zhao… - Antioxidants & redox …, 2013 - liebertpub.com
Aims: To examine if hydrogen sulfide (H2S) can promote glucose uptake and provide
amelioration in type 2 diabetes. Results: Treatment with sodium hydrosulfide (NaHS, an H2S …
amelioration in type 2 diabetes. Results: Treatment with sodium hydrosulfide (NaHS, an H2S …
[HTML][HTML] Hydrogen sulfide: recent progression and perspectives for the treatment of diabetic nephropathy
Diabetic kidney disease develops in approximately 40% of diabetic patients and is a major
cause of chronic kidney diseases (CKD) and end stage kidney disease (ESKD) worldwide …
cause of chronic kidney diseases (CKD) and end stage kidney disease (ESKD) worldwide …
H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression
Y Li, L Li, O Zeng, JM Liu, J Yang - Renal Failure, 2017 - Taylor & Francis
Nephropathy develops in many patients with type 1 diabetes mellitus (T1DM). However, the
specific mechanisms and therapies remain unclear. For this purpose we investigated the …
specific mechanisms and therapies remain unclear. For this purpose we investigated the …
Hydrogen sulfide in diabetic complications: Focus on molecular mechanisms
L Qian, X Liu, Q Chai, R Wang - Endocrine, Metabolic & …, 2018 - ingentaconnect.com
Background: A growing number of studies have indicated that hydrogen sulfide (H2S) affects
the development of diabetes and its complications, but the specific mechanism is not …
the development of diabetes and its complications, but the specific mechanism is not …
Hydrogen sulfide induces heme oxygenase-1 in human kidney cells
E D'Araio, N Shaw, A Millward, A Demaine… - Acta …, 2014 - Springer
Hydrogen sulfide (H 2 S) has been shown to have a potential protective role in a number of
disease states including diabetes and various kidney disorders; however, the mechanisms …
disease states including diabetes and various kidney disorders; however, the mechanisms …
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