Simple Summary Aging affects all cells of the body, leading to impaired system function.
Although scientists are beginning to identify some mechanisms underlying the aging …

The skin is our largest organ and the outermost protective barrier. Its aging reflects both
intrinsic and extrinsic processes resulting from the constant insults it is exposed to. Aging in …

Aging is a universal process that can cause diminished function of organs and various
diseases. The most striking consequences of aging can be seen visibly on the skin, which …

Aged humans display a chronic and low-grade inflammation, termed “inflammaging”, which
has been potentially linked to the subsequent development of some aging-associated …

Cellular senescence and aging result in a reduced ability to manage persistent types of
inflammation. Thus, the chronic low-level inflammation associated with aging phenotype is …

As global life expectancy continues to rise, we are challenged with maintaining health into
old age. One strategy is to target the chronic low-level inflammation associated with aging …

The skin provides the primary protection for the body against external injuries and is
essential in the maintenance of general homeostasis. During ageing, resident cells become …

Significance: Although most researches into the changes in skin with age focus on the
unwelcome aesthetic aspects of the aging skin, skin deterioration with age is more than a …

The expression and treatment of cutaneous disease in the elderly differ from those
applicable to younger adults. Anatomical changes in aging skin result in altered …

Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …