The intricate balance maintained between cell growth and proliferation factors and
apoptosis‐inducing factors is fundamental to the regulation of prostate growth. Disruptions in …

Cancer is one of the leading causes of mortality amongst world's population, in which
prostate cancer is one of the most encountered malignancies among men. Globally, it is the …

Understanding how the regulation of growth factor pathways alters during prostate cancer
(PC) progression may enable researchers to develop targeted therapeutic strategies for …

This article will review the different modes of action of soluble growth factors in the growth of
benign and malignant prostatic cells. Cellular proliferation, growth arrest or even apoptosis …

Treatments that target the androgen axis represent an effective strategy for patients with
advanced prostate cancer, but the disease remains incurable and new therapeutic …

Prostate cancers are genetically and phenotypically heterogenous. The heterogeneous
nature of prostate cancer may be a consequence of mutations in different cell types (basal …

Prostate cancer is a leading cause of death among men in the United States, and currently
early diagnosis and appropriate treatment remain key approaches for patient care …

Prostate adenocarcinoma, the most common tumor occuring among North American men,
preferentially metastasizes to bone, where it characteristically forms osteoblastic lesions …

Prostate cancer progression is often accompanied by alterations of expression in one or
more growth factor receptors and/or their ligands. This commentary examines the hypothesis …

Progression of prostate cancer is accompanied by modifications in the expression of growth
factors and their receptors, many of which are the products of protooncogenes or tumor …