Intermittent fasting improves metabolic flexibility in short-term high-fat diet-fed mice

MA Dedual, S Wueest, M Borsigova… - American journal of …, 2019 - journals.physiology.org
Four days of high-fat diet (HFD) feeding are sufficient to induce glucose intolerance and
hepatic steatosis in mice. While prolonged HFD-induced metabolic complications are partly …

Controlling access time to a high-fat diet during the inactive period protects against obesity in mice

A Haraguchi, N Aoki, T Ohtsu, Y Ikeda… - Chronobiology …, 2014 - Taylor & Francis
Free feeding (FF) with a high fat diet (HFD) causes excessive body weight gain, whereas
restricted feeding (RF) with a HFD attenuates body weight gain. The effects of timing of …

A short bout of HFD promotes long-lasting hepatic lipid accumulation

F Chiazza, TD Challa, FC Lucchini, D Konrad… - Adipocyte, 2016 - Taylor & Francis
abstract A short bout of high fat diet (HFD) impairs glucose tolerance and induces hepatic
steatosis in mice. Here, we aimed to elaborate on long-lasting effects of short-term high fat …

Prolonged fasting induces long-lasting metabolic consequences in mice

JAB Pedroso, F Wasinski, J Donato Jr - The Journal of Nutritional …, 2020 - Elsevier
To endure prolonged fasting, animals undergo important acute physiological adjustments.
However, whether severe fasting also leads to long-term metabolic adaptations is largely …

Obese mice on a high‐fat alternate‐day fasting regimen lose weight and improve glucose tolerance

PMN Joslin, RK Bell, SJ Swoap - Journal of animal physiology …, 2017 - Wiley Online Library
Alternate‐day fasting (ADF) causes body weight (BW) loss in humans and rodents.
However, it is not clear that ADF while maintaining a high‐fat (HF) diet results in weight loss …

[HTML][HTML] Hepatic adaptations to maintain metabolic homeostasis in response to fasting and refeeding in mice

CE Geisler, C Hepler, MR Higgins, BJ Renquist - Nutrition & metabolism, 2016 - Springer
Background The increased incidence of obesity and associated metabolic diseases has
driven research focused on genetically or pharmacologically alleviating metabolic …

Why do mice overeat high‐fat diets? how high‐fat diet alters the regulation of daily caloric intake in mice

JA Licholai, KP Nguyen, WC Fobbs, CJ Schuster… - …, 2018 - Wiley Online Library
Objective Ad libitum high‐fat diets (HFDs) spontaneously increase caloric intake in rodents,
which correlates positively with weight gain. However, it remains unclear why rodents …

Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity

H Chung, W Chou, DD Sears, RE Patterson… - Metabolism, 2016 - Elsevier
Background Menopause is associated with significant hormonal changes that result in
increased total body fat and abdominal fat, amplifying the risk for metabolic syndrome and …

Restricting feeding to the active phase in middle-aged mice attenuates adverse metabolic effects of a high-fat diet

MJ Duncan, JT Smith, J Narbaiza, F Mueez… - Physiology & …, 2016 - Elsevier
Time-restricted feeding ameliorates the deleterious effects of a high-fat diet on body weight
and metabolism in young adult mice. Because obesity is highly prevalent in the middle-aged …

Intermittent fasting reduces body fat but exacerbates hepatic insulin resistance in young rats regardless of high protein and fat diets

S Park, KM Yoo, JS Hyun, S Kang - The Journal of nutritional biochemistry, 2017 - Elsevier
Intermittent fasting (IMF) is a relatively new dietary approach to weight management,
although the efficacy and adverse effects have not been full elucidated and the optimal diets …