Dietary phytochemicals offer protection from oxidative damages and lower the risks of
chronic diseases, by complementary and overlapping action mechanisms. These include …

Altered gap junctional intercellular communication (GJIC) has been associated with
chemical carcinogenesis, where both chemical tumor promoters and chemopreventive …

To develop a strategy for efficacious intervention in order to prevent or treat various cancers,
one must understand the basic mechanism (s) by which various anticancer dietary factors …

Oxidative stress and associated mechanisms involving inflammation, aberrant signaling
pathways and gap junction intercellular communication is increasingly associated with the …

The development of the most efficacious strategy for the prevention and treatment of cancers
is based on understanding the underlying mechanisms of carcinogenesis. This includes the …

Since reactive oxygen species (ROS) play a key role in carcinogenesis, many studies have
focused on the chemopreventive activities of naturally occurring antioxidants. However, the …

In spite of the early speculation by Loewenstein that one of the critical distinguishing
phenotypes of cancers from normal cells was the dysfunction of gap junctional intercellular …

Chemopreventive or chemotherapeutic agents have been those that either kill cancer cells
to a differential degree over the non‐cancer cells or those chemicals that either block the …

Connexin proteins form gap junctions, which permit direct exchange of cytoplasmic contents
between neighboring cells. Evidence indicates that gap junctional intercellular …

Dysregulation of gap junctional intercellular communication (GJIC) has been associated
with different pathologies, including cancer; however, molecular mechanisms regulating …