Spinal serotonergic and kappa opioid receptors mediate facilitation of the tail flick reflex produced by vagal afferent stimulation

K Ren, A Randich, GF Gebhart - Pain, 1991 - Elsevier
Facilitation of the nociceptive tail flick (TF) reflex produced by low intensity (2.0 msec, 20 Hz)
electrical stimulation of cervical vagal afferents (VAS) was studied in rats lightly anesthetized …

Vagal afferent modulation of a nociceptive reflex in rats: involvement of spinal opioid and monoamine receptors

K Ren, A Randich, GF Gebhart - Brain research, 1988 - Elsevier
Modulation of the spinal nociceptive tail flick (TF) reflex by electrical stimulation of
subdiaphragmatic or cervical vagal afferent fibers was characterized in rats lightly …

Spinal serotonergic receptors mediate facilitation of a nociceptive reflex by subcutaneous formalin injection into the hindpaw in rats

AA Calejesan, HC Michael, M Zhuo - Brain research, 1998 - Elsevier
It is documented that spinal nociceptive transmission receives descending facilitatory and
inhibitory modulation from supraspinal structures. The rostral ventral medulla (RVM) …

Characterization of inhibition of a spinal nociceptive reflex by stimulation medially and laterally in the midbrain and medulla in the pentobarbital-anesthetized rat

J Sandkühler, GF Gebhart - Brain research, 1984 - Elsevier
Inhibition of the spinal nociceptive tail flick (TF) reflex by electrical stimulation throughout the
midbrain and medulla was examined and characterized in pentobarbital-anesthetized rats …

Characterization of coeruleospinal inhibition of the nociceptive tail-flick reflex in the rat: mediation by spinal α2-adrenoceptors

SL Jones, GF Gebhart - Brain research, 1986 - Elsevier
Several lines of evidence implicate bulbospinal noradrenergic pathways in antinociception
and descending inhibition. In the present study, descending inhibition of the nociceptive tail …

Medial hypothalamic stimulation suppresses nociceptive spinal dorsal horn neurons but not the tail-flick reflex in the rat

ES Culhane, E Carstens - Brain research, 1988 - Elsevier
This study investigated the potential analgesic effects of medial hypothalamic stimulation
(HS) on a measure of nocifensive behavior (tail-flick test (TF)) in awake rats, and potential …

Stimulation-produced descending inhibition from the periaqueductal gray and nucleus raphe magnus in the rat: mediation by spinal monoamines but not opioids

LD Aimone, SL Jones, GF Gebhart - Pain, 1987 - journals.lww.com
Focal electrical stimulation in the midbrain periaqueductal gray (PAG) or medullary nucleus
raphe magnus (NRM) inhibits spinal nociceptive transmission and nociceptive reflexes. The …

Effects of electrical stimulation of vagal afferents on spinothalamic tract cells in the rat

K Ren, A Randich, GF Gebhart - Pain, 1991 - Elsevier
The effects of electrical stimulation of cervical vagal afferents (VAS) on the background
activity and on the responses of 25 spinothalamic tract (STT) neurons to noxious stimuli …

Stimulation-produced spinal inhibition from the midbrain in the rat is mediated by an excitatory amino acid neurotransmitter in the medial medulla

LD Aimone, GF Gebhart - Journal of Neuroscience, 1986 - Soc Neuroscience
It has been previously established that a bulbar relay plays an important role in descending
inhibition of spinal dorsal horn nociceptive neurons and nociceptive reflexes produced by …

Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus

GF Gebhart, MH Ossipov - Journal of neuroscience, 1986 - Soc Neuroscience
Inhibition of the spinal nociceptive tail-flick (TF) reflex by focal electrical stimulation in the
caudal medulla was examined and characterized in lightly pentobarbital-anesthetized rats …