Mechanisms of Infection by the Human Fungal Pathogen Cryptococcus Neoformans

W Sabiiti, RC May - Future microbiology, 2012 - Taylor & Francis
Brain infection by the fungus Cryptococcus neoformans results in inflammation of the
meninges and brain parenchyma, a condition known as meningoencephalitis. One million …

New insights on the pathogenesis of invasive Cryptococcus neoformans infection

HC Eisenman, A Casadevall, EE McClelland - Current Infectious Disease …, 2007 - Springer
Disseminated cryptococcosis begins with infection of the lungs via inhalation. This is
followed by escape from the lungs and entry into the bloodstream allowing dissemination to …

Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen

Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

[HTML][HTML] Fungal colonization of the brain: anatomopathological aspects of neurological cryptococcosis

AC Colombo, ML Rodrigues - Anais da Academia Brasileira de …, 2015 - SciELO Brasil
Brain infection by the fungus Cryptococcus neoformans results in an estimated 500,000
human deaths per annum. Colonization of the central nervous system (CNS) by C …

The triple threat of cryptococcosis: it's the body site, the strain, and/or the host

JR Perfect - MBio, 2012 - Am Soc Microbiol
Cryptococcosis is the leading invasive fungal infection in the world today. Over the past
century, the causative agents, Cryptococcus neoformans and Cryptococcus gattii, have risen …

Cryptococcal meningitis and anti-virulence therapeutic strategies

K Vu, JA Garcia, A Gelli - Frontiers in microbiology, 2019 - frontiersin.org
Fungal infections of the central nervous system are responsible for significant morbidity and
mortality. Cryptococcus neoformans (Cn) is the primary cause of fungal meningitis. Infection …

Molecular mechanisms of cryptococcal meningitis

TB Liu, DS Perlin, C Xue - Virulence, 2012 - Taylor & Francis
Fungal meningitis is a serious disease caused by a fungal infection of the central nervous
system (CNS) mostly in individuals with immune system deficiencies. Fungal meningitis is …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

The primary target organ of Cryptococcus gattii is different from that of Cryptococcus neoformans in a murine model

P Ngamskulrungroj, Y Chang, E Sionov… - MBio, 2012 - Am Soc Microbiol
Cryptococcosis is caused by the opportunistic pathogen Cryptococcus neoformans or by the
primary pathogen Cryptococcus gattii. Epidemiological studies suggest that patients infected …

Intracellular parasitism of macrophages by Cryptococcus neoformans

M Feldmesser, S Tucker, A Casadevall - Trends in microbiology, 2001 - cell.com
Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …