Recent studies indicate that 40% of chronic myeloid leukemia patients who achieve
sustained undetectable BCR-ABL1 transcripts on tyrosine kinase inhibitor therapy remain …

Background: Current practice guidelines for managing patients with chronic myelogenous
leukemia (CML) call for monitoring BCR-ABL transcript concentrations with a quantitative …

Monitoring BCR-ABL1 fusion transcripts by real-time quantitative RT-PCR has become an
important clinical test for the management of patients with chronic myeloid leukemia …

BACKGROUND AND OBJECTIVE: Capillary electrophoresis (CE) has become an attractive
alternative to SLAB gel analysis for direct and accurate detection of amplified product, and a …

For monitoring minimal residual disease (MRD) in chronic myeloid leukemia (CML) the most
recommended method is quantitative RT-PCR (RT-qPCR) for measuring BCR-ABL1 …

The BCR-ABL1 sequence has advantages over the BCR-ABL1 transcript as a molecular
marker in chronic myeloid leukemia and has been used in research studies. We developed …

Quantitative competitive RT-PCR techniques have been developed to detect BCR-ABL
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …

Monitoring of BCR-ABL transcripts has become established practice in the management of
chronic myeloid leukemia. However, nucleic acid amplification techniques are prone to …

Molecular monitoring for patients with chronic myeloid leukaemia (CML) has become an
important practice in the era of imatinib therapy. For successful widespread introduction into …

Molecular monitoring of chronic myeloid leukaemia (CML) patients by real time quantitative
reverse transcriptase PCR (RQ-PCR) is of clinical value, but the use of diverse laboratory …