LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes

E Martz - Human immunology, 1987 - Elsevier
Adhesions of lymphocytes, among themselves or with other cell types, are necessary for
most steps in immune responses including both induction and effector phases. Among …

[引用][C] The lymphocyte function associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system

TA Springer, ML Dustin, TK Kishimoto… - Annual review of …, 1987 - annualreviews.org
Cell adhesion molecules are thought to play an important role in guiding cell migration and
localization in the development of the embryo and in organogenesis. In the immune system …

LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes.

SJ Mentzer, SH Gromkowski, AM Krensky… - … (Baltimore, Md.: 1950 …, 1985 - journals.aai.org
We report here that MAb to human LFA-1 inhibit spontaneous homotypic adhesions of
human B lymphocytes. This is, to our knowledge, the first report of a MAb that inhibits human …

The lymphocyte function-associated antigen (LFA)-1 and CD2/LFA-3 pathways of antigen-independent human T cell adhesion.

S Shaw, GE Luce - Journal of immunology (Baltimore, Md.: 1950), 1987 - journals.aai.org
Human cytotoxic T lymphocyte clones form conjugates with both antigen-positive and
antigen-negative lymphoblastoid cells. Conjugates with antigen-negative targets form as …

Activation of LFA-1 through a Ca2 (+)-dependent epitope stimulates lymphocyte adhesion.

Y van Kooyk, P Weder, F Hogervorst… - The Journal of cell …, 1991 - rupress.org
The leukocyte function-associated molecule-1 (LFA-1) plays a key role in cell adhesion
processes between cells of the immune system. We investigated the mechanism that may …

The role of lymphocyte function‐associated antigen 1 (LFA‐1) in the adherence of T lymphocytes to B lymphocytes

F Mazerolles, C Lumbroso, O Lecomte… - European journal of …, 1988 - Wiley Online Library
The functional role of the LFA‐1 molecule in the interaction between helper T lymphocytes
and B lymphocytes was investigated using lymphocytes from patients with leukocyte …

The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester.

R Rothlein, TA Springer - The Journal of experimental medicine, 1986 - rupress.org
Lymphocytes become adherent and aggregate after stimulation with phorbol esters such as
PMA. Time-lapse video showed that aggregating cells were motile and exhibited vigorous …

Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.

R Pardi, JR Bender, C Dettori, E Giannazza… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
The role of LFA-1, a member of the integrin supergene family, in intercellular adhesion,
including lymphocyte-endothelial cell (EC) binding, has been established. We now …

On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules.

SC Johnston, ML Dustin, ML Hibbs… - Journal of immunology …, 1990 - journals.aai.org
Species restrictions in immune cell interactions have been demonstrated both in Ag-specific
responses of T lymphocytes and the phenomenon of natural attachment. To determine the …

On the mode of action of LFA-1

CG Figdor, Y van Kooyk, GD Keizer - Immunology today, 1990 - Elsevier
The leukocyte function-associated molecule 1 (LFA-1) plays a key role in cell adhesion
among leukocytes and between leukocytes and other cell types. Although two ligands of …