Abstract 64 Cu-cyclam-RAFT-c (-RGDfK-) 4 is a novel multimeric positron emission
tomography (PET) probe for α V β 3 integrin imaging. Its uptake and α V β 3 expression in …

So far, there is no satisfactory imaging modality to monitor antiangiogenesis therapy of
ovarian cancer noninvasively. The aim of this study was to evaluate the effectiveness and …

Integrin αvβ6 is a cell surface receptor minimally expressed by healthy tissue but elevated in
lung, colon, skin, ovarian, cervical, and pancreatic cancers. A molecular PET agent for …

We have previously labeled cyclic RGD peptide c (RGDyK) with fluorine-18 through
conjugation labeling via a prosthetic 4-[18 F] fluorobenzoyl moiety and applied this [18 F] FB …

Purpose The aim of this study was to evaluate inflammation and tumour imaging with a
vascular adhesion protein 1 (VAP-1) targeting peptide 68 Ga-DOTAVAP-P1 in comparison …

PURPOSE: Growing evidence has demonstrated that aberrant expression of integrin α2β1
might contribute to the invasion, metastasis and drug resistance of non-small cell lung …

Purpose We and others have reported that 18 F-and 64 Cu-labeled arginine–glycine–
aspartate (RGD) peptides allow positron emission tomography (PET) quantification of …

Patients diagnosed with pancreatic cancer at a late stage have a dismal survival rate.
Accurate early detection of pancreatic cancer with a size of 10 mm or less could dramatically …

Purpose The ability of PET to aid in the diagnosis and management of recurrent and/or
disseminated metastatic prostate cancer may be enhanced by the development of novel …

Purpose EMD 121974, a potent cyclic RGD peptide inhibitor of α v-integrins, demonstrated
effectiveness in suppressing brain tumor growth in both preclinical models and phases I/II …