Perfusion of the isolated rat heart under anaerobic conditions inhibited synthesis of whole
heart protein and myosin. The effect was reversible and did not appear to be due to the …

Protein synthesis in heart muscle has been studied in the isolated rat heart perfused with
buffer containing glucose and various amino acid mixtures. The rate of synthesis was …

We measured rates of protein synthesis in vivo in subcellular fractions (soluble, myofibrillar
and stromal fractions) of the heart and the gastrocnemius from rats after fasting or under …

The effect of ischemia on synthesis of myocardial proteins was investigated using a model of
perfusion in which low levels of coronary flow were provided to paced hearts worked against …

Hearts perfused in vitro with buffer containing glucose and amino acids developed a block in
peptide-chain initiation associated with a decline in the rate of protein synthesis, increased …

Cardiac work increased protein synthesis in hearts supplied glucose (mixture 1), glucose-
insulin-glucagon-lactate-beta-hydroxybutyrate (mixture 2) or palmitate-beta-hydroxybutyrate …

The isolated working rat heart preparation was used to study the effects of well defined work
loads on heart protein synthesis. The rate of protein synthesis was evaluated by measuring …

Components of the ribosome cycle, subunits and polysomes, were extracted from heart
muscle and analyzed on exponential sucrose gradients. When MgCl 2 was added in …

Mechanical parameters and intracellular mediators that may control protein synthesis have
been studied in isolated rat hearts subjected to increased aortic pressure or induced to …

The mechanisms involved in hypertrophy of the left ventricle were studied in Langendorff-
perfused rat hearts by measuring the ventricular protein synthesis and its transmural …