Effects of reversible pharmacological shutdown of cerebellar flocculus on the memory of long-term horizontal vestibulo-ocular reflex adaptation in monkeys

M Anzai, H Kitazawa, S Nagao - Neuroscience research, 2010 - Elsevier
The adaptation of the horizontal vestibulo-ocular reflex (HVOR) provides an experimental
model for motor learning. Two studies, using cats and mice, respectively, have recently …

Effects of reversible shutdown of the monkey flocculus on the retention of adaptation of the horizontal vestibulo-ocular reflex

S Nagao, H Kitazawa - Neuroscience, 2003 - Elsevier
There are two different proposals regarding the role of the cerebellar flocculus in the
adaptation of the vestibulo-ocular reflex: that the flocculus is the site for both the induction …

Motor learning in common marmosets: vestibulo-ocular reflex adaptation and its sensitivity to inhibitors of Purkinje cell long-term depression

M Anzai, S Nagao - Neuroscience Research, 2014 - Elsevier
Adaptation of the horizontal vestibulo-ocular reflex (HVOR) provides an experimental model
for cerebellum-dependent motor learning. We developed an eye movement measuring …

Memory trace of motor learning shifts transsynaptically from cerebellar cortex to nuclei for consolidation

F Shutoh, M Ohki, H Kitazawa, S Itohara, S Nagao - Neuroscience, 2006 - Elsevier
Adaptation of ocular reflexes is a prototype of motor learning. While the cerebellum is
acknowledged as the critical site for motor learning, the functional differences between the …

Role of cerebellar cortical protein synthesis in transfer of memory trace of cerebellum-dependent motor learning

T Okamoto, S Endo, T Shirao… - Journal of Neuroscience, 2011 - Soc Neuroscience
We developed a new protocol that induces long-term adaptation of horizontal optokinetic
response (HOKR) eye movement by hours of spaced training and examined the role of …

Memory retention of vestibuloocular reflex motor learning in squirrel monkeys

Y Kuki, Y Hirata, PM Blazquez, SA Heiney… - …, 2004 - journals.lww.com
The vestibuloocular reflex (VOR) motor learning can be induced chronically by wearing
lenses for several weeks to months, or acutely by visual-vestibular mismatch for several …

[引用][C] A neuronal correlate in rabbit's cerebellum to adaptive modification of the vestibulo-ocular reflex

M Dufossé, M Ito, PJ Jastreboff, Y Miyashita - Brain research, 1978 - Elsevier
Adaptation of the horizontal vestibulo-ocular reflex (HVOR) that occurs under sustained
mismatching of vestibular and visual stimuli 4, s, 10, 12 provides a good material for …

Plasticity in the vestibulo-ocular reflex: a new hypothesis.

FA Miles, SG Lisberger - Annual review of neuroscience, 1981 - europepmc.org
The vestibulo-ocular reflex functions to prevent head movements from disturbing retinal
images by generating compensatory eye movements to offset the head movements. In the …

Post-training cerebellar cortical activity plays an important role for consolidation of memory of cerebellum-dependent motor learning

T Okamoto, T Shirao, F Shutoh, T Suzuki, S Nagao - Neuroscience letters, 2011 - Elsevier
Adaptation of mouse horizontal optokinetic response (HOKR) eye movement provides an
experimental model for cerebellum-dependent motor learning. Our previous study revealed …

Ocular reflex adaptation as an experimental model of cerebellar learning––In memory of Masao Ito––

S Nagao - Neuroscience, 2021 - Elsevier
Masao Ito proposed a cerebellar learning hypothesis with Marr and Albus in the early 1970s.
He suggested that cerebellar flocculus (FL) Purkinje cells (PCs), which directly inhibit the …