Among all the human biological fluids used for disease biomarker discovery or clinical
chemistry, urine stands out. It can be collected easily and noninvasively, it is readily …

Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …

Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation
of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this …

Metabolomics is currently being adopted as a tool to understand numerous clinical
pathologies. It is essential to choose the best combination of techniques in order to optimize …

Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

Steps preceding introduction of the analytical sample into individual separation equipment
and/or mass-spectrometry (MS) detectors for targeted or untargeted metabolomics studies …

Currently, most clinical studies in metabolomics only consider a single type of sample such
as urine, plasma, or feces and use a single analytical platform, either NMR or MS. Although …

Urine-based metabolomics-driven strategies for the discovery of biomarkers are increasingly
developed and applied in analytical chemistry. But valid, data-based recommendations for a …

The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …

Metabolomics, focusing on comprehensive analysis of all the metabolites in a biological
system, provides a direct signature of biochemical activity. Using emerging technologies in …