The prevalence of carbapenem‐resistant Gram‐negative bacilli is on the rise worldwide,
posing a major public health threat. Previously, this was mostly a problem in Pseudomonas …

Carbapenemase-producing Enterobacteriaceae (CPE) have spread worldwide, causing
serious infections with increasing frequency. CPE are resistant to almost all available …

The prevalence of carbapenemase-producing Enterobacteriaceae (CPE) has increased
during the past 10 years. Its detection is frequently difficult, because they do not always …

Carbapenem antibiotics are generally considered to be the most potent group of
antimicrobial agents with proven efficacy in the treatment of patients with severe bacterial …

Carbapenems, once considered the last line of defense against of serious infections with
Enterobacteriaceae, are threatened with extinction. The increasing isolation of carbapenem …

The first reports of carbapenem resistance in Enterobacteriaceae isolates occurred in the
early 1990s. Researchers published the first report of an isolate that produced Klebsiella …

Over the past 10 years, dissemination of Klebsiella pneumoniae carbapenemase (KPC) has
led to an increase in the prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in …

Infection with carbapenemase-producing Enterobacteriaceae (CPE) has been shown to
cause significant illness among hospitalized patients. Given the paucity of treatment options …

Carbapenem resistance in gram-negative bacteria has caused a global epidemic that
continues to grow. Although carbapenemase-producing Enterobacteriaceae have received …

Background Carbapenemase-producing enterobacteriaceae (CPE) are a major threat for
severely ill patients. However, only limited data on the epidemiology and on evidence-based …