[HTML][HTML] A high-throughput microplate toxicity screening platform based on Caenorhabditis elegans
J Wu, Y Gao, J Xi, X You, X Zhang, X Zhang… - Ecotoxicology and …, 2022 - Elsevier
Abstract Caenorhabditis elegans (C. elegans), an established model organism, has been
widely used in environmental toxicology research. However, most of the current toxicity …
widely used in environmental toxicology research. However, most of the current toxicity …
A high-throughput assay for the prediction of chemical toxicity by automated phenotypic profiling of Caenorhabditis elegans
S Gao, W Chen, N Zhang, C Xu, H Jing… - JoVE (Journal of …, 2019 - jove.com
Applying toxicity testing of chemicals in higher order organisms, such as mice or rats, is time-
consuming and expensive, due to their long lifespan and maintenance issues. On the …
consuming and expensive, due to their long lifespan and maintenance issues. On the …
Caenorhabditis elegans: a model organism in the toxicity assessment of environmental pollutants
The unfavorable effects of environmental pollutants are becoming increasingly evident. In
recent years, Caenorhabditis elegans (C. elegans) has been used as a powerful terrestrial …
recent years, Caenorhabditis elegans (C. elegans) has been used as a powerful terrestrial …
Caenorhabditis elegans as a tool for environmental risk assessment: emerging and promising applications for a “nobelized worm”
Caenorhabditis elegans has been an invaluable model organism in research fields such as
developmental biology and neurobiology. Neurotoxicity is one of the subfields greatly …
developmental biology and neurobiology. Neurotoxicity is one of the subfields greatly …
An enhanced C. elegans based platform for toxicity assessment
H Xiong, C Pears, A Woollard - Scientific reports, 2017 - nature.com
There is a well-defined regulatory framework governing the approval of chemicals for use as
pharmaceuticals or release into the environment. Toxicity assessment is thus a major hurdle …
pharmaceuticals or release into the environment. Toxicity assessment is thus a major hurdle …
Interlaboratory comparison of a standardized toxicity test using the nematode Caenorhabditis elegans (ISO 10872)
S Höss, W Ahlf, M Bergtold… - Environmental …, 2012 - Wiley Online Library
A ring test was carried out within the standardization process of ISO 10872 to evaluate the
precision of the toxicity test for the nematode Caenorhabditis elegans. Eight different …
precision of the toxicity test for the nematode Caenorhabditis elegans. Eight different …
Feasibility of using a standardized Caenorhabditis elegans toxicity test to assess nanomaterial toxicity
Increasing production and use of engineered nanomaterials (ENMs) has generated
widespread interest in measuring their environmental and human health effects. However …
widespread interest in measuring their environmental and human health effects. However …
Caenorhabditis elegans, a Biological Model for Research in Toxicology
L Tejeda-Benitez, J Olivero-Verbel - Reviews of Environmental …, 2016 - Springer
Caenorhabditis elegans is a nematode widely used as a toxicological model. The
transparency of its body, short lifespan, ability to self-fertilize and ease of culture are …
transparency of its body, short lifespan, ability to self-fertilize and ease of culture are …
Reference Toxicants for Toxicity Testing Using Caenorhabditis Elegans in Aquatic Media
CP Cressman, PL Williams - Environmental …, 1997 - asmedigitalcollection.asme.org
Caenorhabditis elegans aquatic toxicity assays were standardized with five common
reference toxicants: CdC12, NaC1, KC1, sodium lauryl sulfate (SLS), and sodium …
reference toxicants: CdC12, NaC1, KC1, sodium lauryl sulfate (SLS), and sodium …
The C. elegans model in toxicity testing
PR Hunt - Journal of Applied Toxicology, 2017 - Wiley Online Library
Caenorhabditis elegans is a small nematode that can be maintained at low cost and
handled using standard in vitro techniques. Unlike toxicity testing using cell cultures, C …
handled using standard in vitro techniques. Unlike toxicity testing using cell cultures, C …