The oncogenic and tumor suppressive functions of the long noncoding RNA MALAT1: an emerging controversy

Q Chen, C Zhu, Y Jin - Frontiers in genetics, 2020 - frontiersin.org
Long noncoding RNAs are recently emerging as critical factors of tumorigenesis. Originally
regarded as a pre-messenger RNA (mRNA) splicing regulator, the long noncoding RNA …

New Insights into Long Non-Coding RNA MALAT1 in Cancer and Metastasis

Y Sun, L Ma - Cancers, 2019 - mdpi.com
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is one of the most
abundant, long non-coding RNAs (lncRNAs) in normal tissues. This lncRNA is highly …

Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB

V Tripathi, Z Shen, A Chakraborty, S Giri… - PLoS …, 2013 - journals.plos.org
The long noncoding MALAT1 RNA is upregulated in cancer tissues and its elevated
expression is associated with hyper-proliferation, but the underlying mechanism is poorly …

MALAT1 — a paradigm for long noncoding RNA function in cancer

T Gutschner, M Hämmerle, S Diederichs - Journal of molecular medicine, 2013 - Springer
The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a bona fide long
noncoding RNA (lncRNA). MALAT1, also known as nuclear-enriched transcript 2 (NEAT2) …

Clinicopathological and prognostic significance of long noncoding RNA MALAT1 in human cancers: a review and meta-analysis

J Li, Z Cui, H Li, X Lv, M Gao, Z Yang, Y Bi… - Cancer cell …, 2018 - Springer
Background The aberrant regulation of MALAT1 has been indicated to be involved in
various carcinogenic pathways contributing to the tumourigenesis and progression of …

Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer

B Goyal, SRM Yadav, N Awasthee, S Gupta… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a widely
studied lncRNA in cancer. Although dispensable for normal physiology, MALAT1 is …

Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits proliferation, migration, and invasion of esophageal squamous cell carcinoma cells

X Wang, M Li, Z Wang, S Han, X Tang, Y Ge… - Journal of biological …, 2015 - ASBMB
MALAT1, a highly conserved long noncoding RNA, is deregulated in several types of
cancers. However, its role in esophageal squamous cell carcinoma (ESCC) and its …

MALAT1: A long non‑coding RNA highly associated with human cancers

M Zhao, S Wang, Q Li, Q Ji, P Guo… - Oncology …, 2018 - spandidos-publications.com
Metastasis‑associated lung adenocarcinoma transcript 1 (MALAT1), a well‑known lncRNA
associated with numerous diseases, particularly cancer, has received increased attention …

A non‐canonical tumor suppressive role for the long non‐coding RNA MALAT1 in colon and breast cancers

ZH Kwok, V Roche, XH Chew… - … journal of cancer, 2018 - Wiley Online Library
Long noncoding RNAs (lncRNAs) constitute one of the largest classes of transcripts and
have been widely implicated in various diseases such as cancer. Increasing evidence …

[HTML][HTML] Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer

M Jadaliha, X Zong, P Malakar, T Ray, DK Singh… - Oncotarget, 2016 - ncbi.nlm.nih.gov
MALAT1 (metastasis associated lung adenocarcinoma transcript1) is a conserved long non-
coding RNA, known to regulate gene expression by modulating transcription and post …