Synthesis and evaluation of sucrose‐containing polymeric hydrogels for oral drug delivery

KL Shantha, DRK Harding - Journal of applied polymer science, 2002 - Wiley Online Library
Biodegradable and biocompatible copolymeric hydrogels based on sucrose acrylate, N‐
vinyl‐2‐pyrrolidinone, and acrylic acid were designed and synthesized. Because of the …

Preparation and in-vitro evaluation of poly [N-vinyl-2-pyrrolidone-polyethylene glycol diacrylate]-chitosan interpolymeric pH-responsive hydrogels for oral drug …

KL Shantha, DRK Harding - International journal of pharmaceutics, 2000 - Elsevier
Biocompatible and biodegradable pH-responsive hydrogels based on N-vinyl pyrrolidone
(NVP), polyethylene glycol diacrylate (PAC) and chitosan were prepared for controlled drug …

Preparation, swelling characteristics and evaluation of hydrogels for stomach specific drug delivery

P Ravichandran, KL Shantha, KP Rao - International journal of …, 1997 - Elsevier
The development of pH sensitive, biocompatible and biodegradable hydrogels as novel
drug delivery systems was carried out to achieve localized drug delivery. Poly [N-vinyl …

New pH-sensitive glycopolymers for colon-specific drug delivery

M Mahkam - Drug Delivery, 2007 - Taylor & Francis
pH-sensitive hydrogels are suitable candidates for oral delivery of therapeutic peptides,
proteins, and drugs, due to their ability to respond to environmental pH changes. New pH …

A new photocrosslinkable hydrogel based on a derivative of polyaspartic acid for the controlled release of ketoprofen

H Cao, X Ma, S Sun, H Su, T Tan - Polymer bulletin, 2010 - Springer
A novel photocrosslinkable and pH-sensitive hydrogel used for drug delivery was developed
based on polyaspartic acid. Polysuccinimide (PSI) was modified by hydrazine and acryloyl …

Chitosan‐based interpolymeric pH‐responsive hydrogels for in vitro drug release

MY Abdelaal, EA Abdel‐Razik… - Journal of applied …, 2007 - Wiley Online Library
Two series of pH‐responsive biodegradable interpolymeric (IPN) hydrogels based on
chitosan (Ch) and poly (vinyl alcohol)(PVA) were prepared for controlled drug release …

Fabrication of Ph‐responsive hydrogel and its in vitro and in vivo evaluation

UR Tulain, M Ahmad, A Rashid… - Advances in Polymer …, 2018 - Wiley Online Library
The present research work deals with the development of pH‐responsive hydrogel by free
radical polymerization in aqueous media to protect the rabeprazole sodium from acidic …

Water Uptake Behavior of Poly (methacrylamide‐co‐N‐vinyl‐2‐pyrrolidone‐co‐itaconic acid) as pH‐Sensitive Hydrogels: Part I

SK Bajpai, SS Saggu - Journal of Macromolecular Science Part A …, 2006 - Taylor & Francis
Novel hydrogels composed of the three monomers N‐vinyl‐2‐pyrrolidone, methacrylamide
and itaconic acid, have been prepared by free radical aqueous polymerization. The gels …

Preparation and swelling study of a pH-dependent interpolymeric hydrogel based on chitosan for controlled drug release

IM El-Sherbiny, DRK Harding… - International Journal of …, 2006 - Taylor & Francis
Novel pH-dependent, biodegradable interpolymeric network (IPN) hydrogels were prepared
for controlled drug release investigations. The IPN hydrogels were prepared by irradiation of …

Photo‐cross‐linked biodegradable thermo‐and pH‐responsive hydrogels for controlled drug release

C Zhao, P He, C Xiao, X Gao… - Journal of applied …, 2012 - Wiley Online Library
A new strategy was developed to prepare thermo‐and pH‐sensitive hydrogels by the
crosslinking of poly (N‐isopropylacrylamide) with a biodegradable crosslinker derived from …