Acid sphingomyelinase (ASM) cleaves sphingomyelin into the highly lipophilic ceramide,
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …

We read with great interest the correspondence letters of Salles et al.[1] and Stip et al.[2],
following our multicenter observational retrospective study that showed a substantial …

The acid sphingomyelinase/ceramide system plays an important role in bacterial and viral
infections. Here, we report that either pharmacological inhibition of acid sphingomyelinase …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic with severe consequences for afflicted individuals and the society as a whole …

ABSTRACT The Coronavirus Disease 2019 (COVID-19) pandemic caused by the Severe
Acute Respiratory Syndrome Related Coronavirus 2 (SARS-CoV-2) is a global health …

The acid sphingomyelinase/ceramide system has been shown to be important for cellular
infection with at least some viruses, for instance, rhinovirus or severe acute respiratory …

COVID-19 pandemic exerts a health care emergency around the world. The illness severity
is heterogeneous. It is mostly unknown why some individuals who are positive for SARS …

Several medications commonly used for a number of medical conditions share a property of
functional inhibition of acid sphingomyelinase (ASM), or FIASMA. Preclinical and clinical …

The coronavirus disease 2019 (COVID-19) pandemic continues to cause significant
morbidity and mortality worldwide. Since a large portion of the world's population is currently …

The reason behind the high inter-individual variability in response to SARS-CoV-2 infection
and patient's outcome is poorly understood. The present study targets the sphingolipid …