Nephronophthisis (NPHP), an autosomal recessive kidney disease, is the most frequent
genetic cause of end-stage renal failure in the first three decades of life. Positional cloning of …

Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease, represents the
most frequent genetic cause of end-stage kidney disease in the first three decades of life …

Nephronophthisis, an autosomal recessive kidney disease, is the most frequent genetic
cause of chronic renal failure in the first 3 decades of life. Causative mutations in 8 genes …

Nephronophthisis (NPH), an autosomal-recessive tubulointerstitial nephritis, is the most
common cause of hereditary end-stage renal disease in the first three decades of life. Since …

Nephronophthisis is an autosomal recessive cystic kidney disease that leads to renal failure
in childhood or adolescence. Most NPHP gene products form molecular networks. Here we …

Nephronophthisis (NPH) is an autosomal recessive disorder characterized by renal fibrosis,
tubular basement membrane disruption and corticomedullary cyst formation leading to end …

Nephronophthisis (NPHP) is a renal ciliopathy and an autosomal recessive cause of cystic
kidney disease, renal fibrosis, and end-stage renal failure, affecting children and young …

Nephronophthisis (NPH) is an autosomal recessive ciliopathy and a major cause of end-
stage renal disease in children. The main forms, juvenile and adult NPH, are characterized …

Mutations affecting the integrity and function of cilia have been identified in various genes
over the last decade accounting for a group of diseases called ciliopathies. Ciliopathies …

Background Nephronophthisis (NPHP) as a cause of cystic kidney disease is the most
common genetic cause of progressive renal failure in children and young adults. NPHP is …