Metabolic biomarkers for chronic kidney disease

M Breit, KM Weinberger - Archives of biochemistry and biophysics, 2016 - Elsevier
Chronic kidney disease (CKD) is an increasingly recognized burden for patients and health
care systems with high (and growing) global incidence and prevalence, significant mortality …

[HTML][HTML] Chronic Kidney Disease: Underlying Molecular Mechanisms—A Special Issue Overview

L Belo, M Carvalho - International Journal of Molecular Sciences, 2023 - mdpi.com
Chronic kidney disease (CKD) is an epidemic health issue that requires global attention [1].
The worldwide increment of CKD incidence is related to an increase in traditional risk factors …

Genomics and proteomics: how long do we need to reach clinical results?

V Matafora, A Bachi, G Capasso - Blood purification, 2013 - karger.com
Background: Discovery of the ideal biomarker for clinical care remains a major challenge.
Recent progress in genomic and proteomic technologies has allowed the identification of …

Emerging urine-based proteomic biomarkers as valuable tools in the management of chronic kidney disease

P Zürbig, J Siwy, H Mischak - Expert Review of Molecular …, 2019 - Taylor & Francis
The World Health Organization has estimated mortality and burden of chronic kidney
disease (CKD) in 2002 and predicted it will rank 13th in 2030 instead of 17th in 2002 among …

Targeted biomarkers of progression in chronic kidney disease

EP Owens, HG Healy, DA Vesey, WE Hoy, GC Gobe - Clinica Chimica Acta, 2022 - Elsevier
Background Chronic kidney disease (CKD) is an increasingly significant health issue
worldwide. Early stages of CKD can be asymptomatic and disease trajectory difficult to …

Omics research in diabetic kidney disease: new biomarker dimensions and new understandings?

N Tofte, F Persson, P Rossing - Journal of nephrology, 2020 - Springer
The use of “omics” is increasing in research areas looking to identify biomarkers or early
preclinical signs of disease or to increase understanding of complex pathological processes …

Chronic kidney disease and the search for new biomarkers for early diagnosis

AL Saucedo, MM Perales-Quintana… - Current Medicinal …, 2018 - ingentaconnect.com
Chronic kidney disease (CKD) is a progressive condition characterized by a permanent and
irreversible loss of renal function. In accordance to international guidelines, CKD clinical …

Understanding glomerular diseases through proteomics

E Mavrogeorgis, H Mischak, J Beige… - Expert Review of …, 2021 - Taylor & Francis
Introduction Chronic kidney disease is avery common and complex chronic disease.
Uncovering the pathological patterns of CKD on the molecular level of bio-fluids and tissue …

[HTML][HTML] Biomarkers in clinical epidemiology studies

C Zoccali, G Tripepi, V Stel, EL Fu… - Clinical Kidney …, 2024 - academic.oup.com
This paper discusses the use of biomarkers in clinical practice and biomedical research.
Biomarkers are measurable characteristics that can be used to indicate the presence or …

Clinical usefulness of novel prognostic biomarkers in patients on hemodialysis

A Ortiz, ZA Massy, D Fliser, B Lindholm… - Nature Reviews …, 2012 - nature.com
Prognosis, risk stratification and monitoring the effects of treatment are fundamental
elements in the decision-making process when implementing prevention strategies for …