Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA

S Fang, X Huang, X Zhang, M Zhang… - Proceedings of the …, 2021 - National Acad Sciences
SbtA is a high-affinity, sodium-dependent bicarbonate transporter found in the
cyanobacterial CO2-concentrating mechanism (CCM). SbtA forms a complex with SbtB …

Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB

XY Liu, WT Hou, L Wang, B Li, Y Chen, Y Chen… - Cell Discovery, 2021 - nature.com
Dear Editor, Carbon and nitrogen, the uptake and intracellular metabolisms of which are
tightly coupled 1, are the two most fundamental nutrients for all living organisms. As one of …

Membrane topology of the cyanobacterial bicarbonate transporter, SbtA, and identification of potential regulatory loops

GD Price, MC Shelden, SM Howitt - Molecular membrane biology, 2011 - Taylor & Francis
The transporter SbtA is a high affinity Na+-dependent HCO3-uptake system present in a
majority of cyanobacterial clades. It functions in conjunction with CO2 uptake systems and …

Characterisation of Cyanobacterial Bicarbonate Transporters in E. coli Shows that SbtA Homologs Are Functional in This Heterologous Expression System

J Du, B Förster, L Rourke, SM Howitt, GD Price - PloS one, 2014 - journals.plos.org
Cyanobacterial HCO3-transporters BCT1, SbtA and BicA are important components of
cyanobacterial CO2-concentration mechanisms. They also show potential in applications …

Structural mechanism of the active bicarbonate transporter from cyanobacteria

C Wang, B Sun, X Zhang, X Huang, M Zhang, H Guo… - Nature plants, 2019 - nature.com
Bicarbonate transporters play essential roles in pH homeostasis in mammals and
photosynthesis in aquatic photoautotrophs. A number of bicarbonate transporters have been …

Structural Basis for the Allosteric Regulation of the SbtA Bicarbonate Transporter by the PII-like Protein, SbtB, from Cyanobium sp. PCC7001

JA Kaczmarski, NS Hong, B Mukherjee, LT Wey… - Biochemistry, 2019 - ACS Publications
Cyanobacteria have evolved a suite of enzymes and inorganic carbon (Ci) transporters that
improve photosynthetic performance by increasing the localized concentration of CO2 …

Genes essential to sodium-dependent bicarbonate transport in cyanobacteria: function and phylogenetic analysis

M Shibata, H Katoh, M Sonoda, H Ohkawa… - Journal of Biological …, 2002 - ASBMB
The cyanobacterium Synechocystis sp. strain PCC 6803 possesses two CO 2 uptake
systems and two HCO 3− transporters. We transformed a mutant impaired in CO 2 uptake …

Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA

KA Selim, M Haffner, O Mantovani… - Proceedings of the …, 2023 - National Acad Sciences
The PII superfamily consists of widespread signal transduction proteins found in all domains
of life. In addition to canonical PII proteins involved in C/N sensing, structurally similar PII …

The structure of a cyanobacterial bicarbonate transport protein, CmpA

NM Koropatkin, DW Koppenaal, HB Pakrasi… - Journal of Biological …, 2007 - ASBMB
Cyanobacteria, blue-green algae, are the most abundant autotrophs in aquatic
environments and form the base of the food chain by fixing carbon and nitrogen into cellular …

Structure, function and regulation of the cyanobacterial high-affinity bicarbonate transporter, BCT1

T Omata, Y Takahashi, O Yamaguchi… - Functional plant …, 2002 - CSIRO Publishing
The cmpABCD operon of the cyanobacterium Synechococcus sp. strain PCC7942, which is
transcribed specifically under CO2-limited growth conditions, encodes an ATP-binding …