Objective: To evaluate the concept of relative adrenal insufficiency necessitating
corticosteroid therapy in septic shock. Design: Retrospective study. Setting: Medical-surgical …

Objective To determine whether a baseline (random) cortisol concentration< 25 μg/dL in
patients with septic shock was a better discriminator of adrenal insufficiency than the …

Objective: To compare a low-dose (1 μg) corticotropin stimulation test with the more
standard (250 μg) test for the diagnosis of relative adrenal insufficiency. Design: Diagnostic …

Objective: To examine recent literature regarding corticotherapy in critically ill patients
suffering from sepsis, acute respiratory distress syndrome (ARDS), and severe community …

Objective: To refine the value of baseline and adrenocorticotropin hormone (ACTH)-
stimulated cortisol levels in relation to mortality from severe sepsis or septic shock. Design …

Adequate adrenocortical function is essential to survive critical illness. Most critically ill
patients display an elevated plasma cortisol level, reflecting activation of the pituitary …

The use of corticosteroids in patients with sepsis and septic shock has been controversial for
decades [1]. Based primarily on the Schumer study [2], high doses of glucocorticoids …

Purpose To study the value of free versus total cortisol levels in assessing relative adrenal
insufficiency during critical illness-related corticosteroid insufficiency. Methods A prospective …

Methods: Between July, 2005, and June, 2006, 82 patients were prospectively enrolled in
the study if they met the criteria of septic shock and relative adrenal insufficiency. All patients …

IMPLICATIONS: In this prospective study two consecutive adrenocorticotropic hormone
(ACTH) stimulation tests were performed in 60 critically ill patients. In a subgroup of septic …