Strategies for the synthesis of indole diketopiperazine alkaloids (indole DKPs) have been
described and involve three analogs of indole DKPs. The antimicrobial activity and structure …

Some novel benzimidazole derivatives were synthesized and their antimicrobial activities
were evaluated. Compounds 3a and 3b exhibited excellent antibacterial activity with MIC …

Herein, we describe the successful design and synthesis of seventeen new 1, 4-diazinanes,
compounds commonly known as piperazines. This group of piperazine derivatives (3a-q) …

FabH, β-ketoacyl-acyl carrier protein (ACP) synthase III, is critically important to the initiation
of fatty acid biosynthesis and is highly conserved among Gram-positive and Gram-negative …

Nitroimidazoles and their derivatives have drawn continuing interest over the years because
of their varied biological activities, recently found application in drug development for …

Novel xanthine and imidazolone derivatives were synthesized based on oxazolone
derivatives 2a-c as a key intermediate. The corresponding xanthine 3-5 and imidazolone …

Because of the growing bacterial resistance to antibiotics, the discovery of new antibiotics is
critical. The search for new antimicrobial drugs that are effective in treating new and existing …

Herein, novel three series of benzimidazole scaffold bearing hydrazone, 1, 2, 4-triazole and
1, 3, 4-oxadiazole moieties 1-3, 4a-j, 6a-c and 7 derivatives were designed, synthesized and …

In this research, previously and newly synthesized 5-amino-2-(4-substitutedphenyl/benzyl)
benzoxazoles (3a–3l) and 2-substituted-5-(4-nitro/aminophenylsulfonamido) benzoxazoles …

Background: Novel bis (1, 4-dihydropyridine) derivatives linked to arene core via ester 5-7
as well as ether linkages 10-12 were prepared, and their structures were confirmed by …