As a naturally wide distributed flavone, chrysin exhibits numerous biological activities
including anticancer, anti-inflammatory, and antimicrobials activities. β-Ketoacyl-acyl carrier …

In search of novel biologically potent compounds, three novel organic molecules have been
synthesized. The structures of the prepared compounds have been characterized by …

A very practical method for the synthesis of unsymmetrical carbamide derivatives in good to
excellent yield was presented, without the need for any catalyst and at room temperature …

Abstract A series of 1, 3-diaryl-2-propen-1-ones and their indole analogs were synthesized
and evaluated for antibacterial activity. Structures of newly synthesized compounds were …

The Bcl-2 protein has a vital function in controlling the programmed cell doom of
mitochondria. If programmed cell death signals are obstructed, an imbalance between cell …

Purpose There is an urgent need to discover and develop new drugs to combat
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB) in humans. In recent …

Development of new drugs is one of the solutions to fight against the existing antimicrobial
resistance threat. Cinnamaldehyde-amino acid Schiff base compounds, are newly …

The enzyme FabH catalyzes the initial step of fatty acid biosynthesis via a type II fatty acid
synthase. The pivotal role of this essential enzyme combined with its unique structural …

One of the best ways to design new biocidal agents is synthesizing hybrid molecules by
combining two or more bioactive moieties in a single molecular scaffold. So, new series of …

In this study, we have investigated small multitargeted molecules containing 2-
aminopyrimidine scaffold that may further act as precursor for developing more potent …