The ultrastructure of the beta granules is distinctly different in the islets of the rat, dog, cat,
rabbit, guinea pig and chicken. The variations are so characteristic that each species can be …

The islets of Langerhans in normal and obese-hyperglycemic mice were studied by electron
microscopy. Two different types of islet cells with ultrastructural features well distinguished …

Electron microscopic criteria have been established for the identification of all the different
types of islet cells. A remarkable difference in the ultrastructure of beta granules has been …

A partially purified secretory granule fraction, isolated from rat islets of Langerhans by
differential centrifugation, was used for investigating the stability of the beta granules during …

A method has been devised for the isolation of a secretory granule fraction from isolated rat
islets of Langerhans. The islets were homogenized in buffered sucrose, and the …

The electron microscopic study of rabbit pancreatic islets reveals in adthtiun to alpha anti
beta cells a third cell type containing specific secretory graaules. This third cell is considered …

SUMMARY β-cell secretory granules generally are considered to be the numerous diffusely
distributed cytoplasmic single membrane limited vacuoles with electron dense central body …

Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic
acid had, in negatively stained images, a 50-A periodicity. This periodicity was also …

The distribution of radioautographic grains over organelles within the beta cells of rat islets
of Langerhans was investigated at various times after pulse labeling of the isolated islets …

Light-and electron-microscopic observations were made on the alpha, beta and delta cells
of the pancreatic islets of the domestic fowl and on their cytologic changes following the …