Disturbed microbial ecology in Alzheimer's disease: Evidence from the gut microbiota and fecal metabolome

J Xi, D Ding, H Zhu, R Wang, F Su, W Wu, Z Xiao… - BMC microbiology, 2021 - Springer
Background Gut microbiota (GMB) alteration has been reported to influence the Alzheimer's
disease (AD) pathogenesis through immune, endocrine, and metabolic pathways. This study …

Gut microbiome alterations in preclinical Alzheimer's disease

JH Jung, G Kim, MS Byun, JH Lee, D Yi, H Park… - PLoS …, 2022 - journals.plos.org
Background Although some human studies have reported gut microbiome changes in
individuals with Alzheimer's disease (AD) dementia or mild cognitive impairment (MCI), gut …

Gut microbiome dysbiosis in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis

S Jemimah, CMM Chabib, L Hadjileontiadis… - PLoS …, 2023 - journals.plos.org
Background Alzheimer's disease (AD) is a neurodegenerative disorder that causes gradual
memory loss. AD and its prodromal stage of mild cognitive impairment (MCI) are marked by …

Gut microbiome alterations in Alzheimer's disease

NM Vogt, RL Kerby, KA Dill-McFarland, SJ Harding… - Scientific reports, 2017 - nature.com
Alzheimer's disease (AD) is the most common form of dementia. However, the
etiopathogenesis of this devastating disease is not fully understood. Recent studies in …

Multi-omics data reveals aberrant gut microbiota-host glycerophospholipid metabolism in association with neuroinflammation in APP/PS1 mice

X Qian, W Hai, S Chen, M Zhang, X Jiang, H Tang - Gut Microbes, 2023 - Taylor & Francis
Numerous studies have described the notable impact of gut microbiota on the brain in
Alzheimer's disease (AD) via the gut–brain axis. However, the molecular mechanisms …

Gut microbiota changes and their correlation with cognitive and neuropsychiatric symptoms in Alzheimer's disease

Y Zhou, Y Wang, M Quan, H Zhao… - Journal of Alzheimer's …, 2021 - content.iospress.com
Background: Gut microbiota can influence human brain function and behavior. Recent
studies showed that gut microbiota might play an important role in the pathogenesis of …

Altered gut microbial metabolites in amnestic mild cognitive impairment and Alzheimer's disease: signals in host–microbe interplay

L Wu, Y Han, Z Zheng, G Peng, P Liu, S Yue, S Zhu… - Nutrients, 2021 - mdpi.com
Intimate metabolic host–microbiome crosstalk regulates immune, metabolic, and neuronal
response in health and disease, yet remains untapped for biomarkers or intervention for …

The potential role of gut microbiota in Alzheimer's disease: from diagnosis to treatment

A Varesi, E Pierella, M Romeo, GB Piccini, C Alfano… - Nutrients, 2022 - mdpi.com
Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …

Combination of gut microbiota and plasma amyloid-β as a potential index for identifying preclinical Alzheimer's disease: a cross-sectional analysis from the SILCODE …

C Sheng, K Yang, B He, W Du, Y Cai, Y Han - Alzheimer's research & …, 2022 - Springer
Background Plasma amyloid-β (Aβ) may facilitate identification of individuals with brain
amyloidosis. Gut microbial dysbiosis in Alzheimer's disease (AD) is increasingly being …

Gut microbiome, cognitive function and brain structure: a multi-omics integration analysis

X Liang, Y Fu, W Cao, Z Wang, K Zhang… - Translational …, 2022 - Springer
Background Microbiome-gut-brain axis may be involved in the progression of age-related
cognitive impairment and relevant brain structure changes, but evidence from large human …