Althoughin vitrosystems have provided important information about the composition and
nature of various immune responses, understanding physiologically relevant function and …

Although the role of natural killer (NK) cells in defense against certain viral infections has
been appreciated for a number of years, characterization of the virus-induced endogenous …

▪ Abstract Natural killer (NK) cells are populations of lymphocytes that can be activated to
mediate significant levels of cytotoxic activity and produce high levels of certain cytokines …

At early times during viral infec-tions, natural killer (NK) cells can contribute to direct antiviral
defense (1, 2). The effect is most dramatic when they are stimulated to release the contents …

Because of their ability to mediate cell lysis and produce cytokines, natural killer (NK) cells
have the potential to contribute to either beneficial or detrimental effects in the host [l-lo] …

Cytokines are involved in directing the activation of natural killer (NK) cells. NK cells are
involved in the recognition of cells that have been altered; thus they do not recognize …

Natural killer (NK) cells play a key role in innate host defense against viruses. Significant
progress has been made in understanding the specific response of NK cells during viral …

Cytokines are soluble and membrane-bound factors that dictate immune responses.
Dogmatically, cytokines are divided into families that promote type 1 cell-mediated immune …

Natural killer (NK) cells provide a first line of defense against infection via the production of
antiviral cytokines and direct lysis of target cells. Cytokines such as interleukin 12 (IL-12) …

Increasing evidence indicates the importance of human natural killer (NK) cells in the
immune response against certain viral infections. In the present article, we summarize …