Inflammatory disequilibrium in stroke
D Petrovic-Djergovic, SN Goonewardena… - Circulation …, 2016 - Am Heart Assoc
Over the past several decades, there have been substantial advances in our knowledge of
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …
Systemic immune activation shapes stroke outcome
Stroke is a major cause of morbidity and mortality, and activation of the immune system can
impact on stroke outcome. Although the majority of research has focused on the role of the …
impact on stroke outcome. Although the majority of research has focused on the role of the …
Immune responses to stroke: mechanisms, modulation, and therapeutic potential
C Iadecola, MS Buckwalter… - The Journal of clinical …, 2020 - Am Soc Clin Investig
Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Post-stroke inflammation—target or tool for therapy?
KL Lambertsen, B Finsen, BH Clausen - Acta neuropathologica, 2019 - Springer
Inflammation is currently considered a prime target for the development of new stroke
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …
[HTML][HTML] Inflammation and stroke: an overview
J Anrather, C Iadecola - Neurotherapeutics, 2016 - Elsevier
The immune response to acute cerebral ischemia is a major factor in stroke pathobiology
and outcome. While the immune response starts locally in occluded and hypoperfused …
and outcome. While the immune response starts locally in occluded and hypoperfused …
Systemic inflammation after stroke: implications for post‐stroke comorbidities
Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …
research, and the modulation of neuroinflammatory pathways has been identified as a …
Filling the gaps on stroke research: Focus on inflammation and immunity
D Levard, I Buendia, A Lanquetin, M Glavan… - Brain, behavior, and …, 2021 - Elsevier
For the last two decades, researchers have placed hopes in a new era in which a
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …
Inflammatory responses after ischemic stroke
JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …
tissue repair. This is a complex process involving a range of cell types and effector …
Inflammatory mechanisms in ischemic stroke: therapeutic approaches
SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
Targeting the immune system for ischemic stroke
Stroke is responsible for almost 6 million deaths and more than 10% of all mortalities each
year, and two-thirds of stroke survivors remain disabled. With treatments for ischemic stroke …
year, and two-thirds of stroke survivors remain disabled. With treatments for ischemic stroke …