Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …

Approaches for the effective management of acute stroke are sparse, and many measures
for brain protection fail. However, our ability to modulate the immune system and modify the …

Stroke is a disease that occurs due to a sudden interruption of the blood supply to the brain.
It is a leading cause of death and disability worldwide. It is well-known that the immune …

Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …

Cerebral postischemic reperfusion injury is defined as deterioration of ischemic brain tissue
that parallels and antagonizes the benefits of restoring cerebral circulation after therapeutic …

The secondary neuroinflammatory response has come into focus of experimental stroke
research. Immunological mechanisms after acute stroke are being investigated in the hope …

The role of immunity in all stages of stroke is increasingly being recognized, from the
pathogenesis of risk factors to tissue repair, leading to the investigation of a range of …

Stroke affects the normally well-balanced interplay of the 2 supersystems: the nervous and
the immune system. Recent research elucidated some of the involved signals and …

Ischemic stroke is characterized by the disruption of cerebral blood flow (CBF). This
reduction of CBF results in energy failure and secondary biochemical disturbances, eliciting …

Inflammation is a defense reaction against diverse insults that serves to remove noxious
agents and to limit their detrimental effects. There is increasing evidence that post-ischemic …