Ischemic stroke, caused by a sudden disruption of blood flow to the brain, is a leading cause
of death and exerts a heavy burden on both patients and public health systems. Currently …

Immune mechanisms of stroke : Current Opinion in Neurology Immune mechanisms of
stroke : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get …

Inhibiting inflammation following both ischemic and hemorrhagic stroke remains a promising
approach. More sophisticated therapies, with pleiotropic beneficial effects, and more …

Although several studies have suggested that anti-inflammatory strategies reduce
secondary infarct growth in animal stroke models, clinical studies have not yet demonstrated …

Cerebral inflammation is a promising therapeutic target for ischaemic stroke. After ischaemic
stroke, inflammatogenic self-molecules, which originate from damaged brain tissue due to …

Stroke is one of the leading causes of mortality and morbidity. The stroke process triggers an
inflammatory reaction that may last up to several months. Suppression of inflammation using …

Despite extensive research into stroke pathology, there have not been any major recent
advancements in stroke therapeutics. Animal models of cerebral ischemia and clinical data …

The profound damage to the CNS caused by ischemic lesions has been well documented.
Yet, relatively little is known about the contribution to and effects on the immune system …

Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …

Background and Purpose—Ischemic stroke leads to significant morbidity and mortality in the
Western world. Early reperfusion strategies remain the treatment of choice but can initiate …