Immune cell infiltration into the brain after ischemic stroke in humans compared to mice and rats: a systematic review and meta-analysis
C Beuker, JK Strecker, R Rawal… - Translational stroke …, 2021 - Springer
Although several studies have suggested that anti-inflammatory strategies reduce
secondary infarct growth in animal stroke models, clinical studies have not yet demonstrated …
secondary infarct growth in animal stroke models, clinical studies have not yet demonstrated …
T cell response in ischemic stroke: from mechanisms to translational insights
D Zhang, J Ren, Y Luo, Q He, R Zhao, J Chang… - Frontiers in …, 2021 - frontiersin.org
Ischemic stroke, caused by a sudden disruption of blood flow to the brain, is a leading cause
of death and exerts a heavy burden on both patients and public health systems. Currently …
of death and exerts a heavy burden on both patients and public health systems. Currently …
Suppression of inflammation in ischemic and hemorrhagic stroke: therapeutic options
TJ Kleinig, R Vink - Current opinion in neurology, 2009 - journals.lww.com
Inhibiting inflammation following both ischemic and hemorrhagic stroke remains a promising
approach. More sophisticated therapies, with pleiotropic beneficial effects, and more …
approach. More sophisticated therapies, with pleiotropic beneficial effects, and more …
Immune mechanisms of stroke
T Magnus, H Wiendl, C Kleinschnitz - Current opinion in …, 2012 - journals.lww.com
Immune mechanisms of stroke : Current Opinion in Neurology Immune mechanisms of
stroke : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get …
stroke : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get …
Cellular and molecular mechanisms of sterile inflammation in ischaemic stroke
K Nakamura, T Shichita - The journal of biochemistry, 2019 - academic.oup.com
Cerebral inflammation is a promising therapeutic target for ischaemic stroke. After ischaemic
stroke, inflammatogenic self-molecules, which originate from damaged brain tissue due to …
stroke, inflammatogenic self-molecules, which originate from damaged brain tissue due to …
Molecular and cellular immune responses to ischemic brain injury
HA Seifert, KR Pennypacker - Translational stroke research, 2014 - Springer
Despite extensive research into stroke pathology, there have not been any major recent
advancements in stroke therapeutics. Animal models of cerebral ischemia and clinical data …
advancements in stroke therapeutics. Animal models of cerebral ischemia and clinical data …
Inflammation following stroke
MN Perera, HK Ma, S Arakawa, DW Howells… - Journal of Clinical …, 2006 - Elsevier
Stroke is one of the leading causes of mortality and morbidity. The stroke process triggers an
inflammatory reaction that may last up to several months. Suppression of inflammation using …
inflammatory reaction that may last up to several months. Suppression of inflammation using …
Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression
H Offner, AA Vandenbark, PD Hurn - Neuroscience, 2009 - Elsevier
The profound damage to the CNS caused by ischemic lesions has been well documented.
Yet, relatively little is known about the contribution to and effects on the immune system …
Yet, relatively little is known about the contribution to and effects on the immune system …
Role of inflammation and its mediators in acute ischemic stroke
Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …
[HTML][HTML] Immune pathway activation in neurons triggers neural damage after stroke
D Wu, J Liu, J Liu, W Ge, S Wu, C Zeng, J Liang, KJ Liu… - Cell Reports, 2023 - cell.com
Ischemic brain injury is a severe medical condition with high incidences in elderly people
without effective treatment for the resulting neural damages. Using a unilateral mouse stroke …
without effective treatment for the resulting neural damages. Using a unilateral mouse stroke …