Inflammatory and immune responses play important roles following ischaemic stroke.
Inflammatory responses contribute to damage and also contribute to repair. Injury to tissue …

Ischemic stroke is one of the leading health issues and the major cause of permanent
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …

Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

Despite decades of promising preclinical validation and clinical translation, ischemic stroke
still remains as one of the leading causes of death and disability worldwide. Within its …

Through considerable effort in research and clinical studies, the immune system has been
identified as a participant in the onset and progression of brain injury after ischaemic stroke …

This review covers the pathogenesis of ischemic stroke and future directions regarding
therapeutic options after injury. Ischemic stroke is a devastating disease process affecting …

Stroke is the third leading cause of death in industrialized countries and one of the largest
causes of permanent disability worldwide. Therapeutic options to fight stroke are still limited …

So far, intravenous tissue-type plasminogen activator (tPA) and mechanical removal of
arterial blood clot (thrombectomy) are the only available treatments for acute ischemic …

In experimental models of stroke, inflammation appears to contribute to cerebral ischemic
injury. Clinical trials that are aimed at limiting the postischemic inflammatory response …

Stroke represents devastating pathology which is associated with a high morbidity and
mortality. Initial damage caused directly by the onset of stroke, primary injury, may be …