Fetal intrauterine growth restriction (IUGR) is a frequently occurring and serious
complication of pregnancy. Infants exposed to IUGR are at risk for numerous perinatal …

Fetal intrauterine growth restriction (IUGR) is a frequently occurring and serious
complication of pregnancy. Infants exposed to IUGR are at risk for numerous perinatal …

The mechanisms underlying reduced fetal growth in response to maternal protein restriction
are not well established. Maternal levels of insulin, IGF-I, and leptin are decreased in rats fed …

Intrauterine growth restriction (IUGR) impairs insulin secretion in humans and in animal
models of IUGR. Several underlying mechanisms have been implicated, including …

Intrauterine growth restriction (IUGR) has been defined in several ways, but in general
describes a condition in which the fetus exhibits poor growth in utero. This complication of …

Placental insufficiency is a primary cause of intrauterine growth restriction (IUGR). IUGR
increases the risk of developing type 2 diabetes mellitus (T2DM) throughout life, which …

Epidemiological and experimental studies have demonstrated that early postnatal nutrition
has been associated with long-term effects on glucose homeostasis in adulthood. Recently …

We determined in vivo and in vitro pancreatic islet insulin secretion and glucose metabolism
in fetuses with intrauterine growth restriction (IUGR) caused by chronic placental …

Intrauterine growth restriction (IUGR) increases the risk for metabolic disease and diabetes,
although the developmental origins of this remain unclear. We measured glucose …

Glucose is the major fuel for fetal oxidative metabolism. A positive maternal–fetal glucose
gradient drives glucose across the placenta and is sufficient to meet the demands of the …