The role of urotensin-II in obesity and metabolic syndrome in pediatric population

M Simunovic, A Jukic, M Paradzik, D Supe-Domic… - Children, 2022 - mdpi.com
Background: Urotensin-II (U-II) is a short cyclic peptide that is widely recognized as one of
the most potent vasoconstrictors. U-II plays a role in the pathophysiology of MS, participating …

Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study

H Xie, X Wang, Y He, D Huang, X Qu… - International Journal …, 2020 - Wiley Online Library
Up to date, human urotensin II (UII) is the most potent vasoconstrictor in mammalian
animals. To explore whether UII played an important role in the development of …

Raised plasma urotensin II in type 2 diabetes patients is associated with the metabolic syndrome phenotype

D Gruson, MF Rousseau… - The Journal of …, 2010 - Wiley Online Library
J Clin Hypertens (Greenwich). 2010; 12: 653–660.© 2010 Wiley Periodicals, Inc. Urotensin II
(UII) exerts multiple effects on the cardiovascular system, acts as a diabetogenic agent, and …

A closer look at the role of urotensin II in the metabolic syndrome

PO Barrette, AG Schwertani - Frontiers in endocrinology, 2012 - frontiersin.org
Urotensin II (UII) is a vasoactive peptide that was first discovered in the teleost fish, and later
in mammals and humans. UII binds to the G protein coupled receptor GPR14 (now known as …

Urotensin II and cardiovascular diseases

G Thanassoulis, T Huyhn, A Giaid - Peptides, 2004 - Elsevier
Urotensin II (UII) has been found to be a potent vasoactive peptide in humans and in a
number of relevant animal models of cardiovascular disease such as the mouse, rat and …

The role of urotensin II in the metabolic syndrome

KL Ong, LYF Wong, BMY Cheung - Peptides, 2008 - Elsevier
Urotensin II is a potent vasoconstrictive peptide that mediates both endothelium-
independent vasoconstriction and endothelium-dependent vasodilatation. Its plasma level …

Plasma Urotensin II levels in children and adolescents with chronic kidney disease: a single-centre study

A Garoufi, S Drapanioti, A Marmarinos, V Askiti… - BMC nephrology, 2017 - Springer
Abstract Background Increased plasma Urotensin II (UII) levels have been found in adults
with renal diseases. Studies in children are scarce. The objective of the study is to estimate …

Human urotensin II and metabolic syndrome

T Watanabe, T Kanome, T Suguro… - Vascular Disease …, 2006 - ingentaconnect.com
Human urotensin II (U-II), the most potent vasoconstrictor peptide identified to date, and its
receptor (UT) are involved in atherosclerosis. U-II is expressed in endothelial cells …

Role of urotensin II in health and disease

B Ross, K McKendy, A Giaid - American Journal of …, 2010 - journals.physiology.org
Urotensin II (UII) is an 11 amino acid cyclic peptide originally isolated from the goby fish. The
amino acid sequence of UII is exceptionally conserved across most vertebrate taxa, sharing …

Association between human urotensin II and essential hypertension—a 1: 1 matched case-control study

H Peng, M Zhang, X Cai, J Olofindayo, A Tan… - PLoS One, 2013 - journals.plos.org
Objective We aimed to evaluate the controversial association between human urotensin II
and essential hypertension in untreated hypertensive cases and normotensive controls …