A neuro-immune, neuro-oxidative and neuro-nitrosative model of prenatal and postpartum depression
A large body of evidence indicates that major affective disorders are accompanied by
activated neuro-immune, neuro-oxidative and neuro-nitrosative stress (IO&NS) pathways …
activated neuro-immune, neuro-oxidative and neuro-nitrosative stress (IO&NS) pathways …
The immune system and the role of inflammation in perinatal depression
P Leff-Gelman, I Mancilla-Herrera, M Flores-Ramos… - Neuroscience …, 2016 - Springer
Major depression during pregnancy is a common psychiatric disorder that arises from a
complex and multifactorial etiology. Psychosocial stress, sex, hormones, and genetic …
complex and multifactorial etiology. Psychosocial stress, sex, hormones, and genetic …
Postpartum depression: psychoneuroimmunological underpinnings and treatment
G Anderson, M Maes - Neuropsychiatric Disease and Treatment, 2013 - Taylor & Francis
Postpartum depression (PPD) is common, occurring in 10%–15% of women. Due to
concerns about teratogenicity of medications in the suckling infant, the treatment of PPD has …
concerns about teratogenicity of medications in the suckling infant, the treatment of PPD has …
Natural regulatory IgM‐mediated autoimmune responses directed against malondialdehyde regulate oxidative and nitrosative pathways and coupled with IgM …
C Roomruangwong, DS Barbosa… - Psychiatry and …, 2018 - Wiley Online Library
Aim We aimed to delineate the effects of immunoglobulin (Ig) M‐mediated autoimmune
responses directed against malondialdehyde (MDA) and nitroso (SNO) adducts on nitro …
responses directed against malondialdehyde (MDA) and nitroso (SNO) adducts on nitro …
[HTML][HTML] The cytokine, chemokine, and growth factor network of prenatal depression
M Maes, Y Abe, W Sirichokchatchawan… - Brain sciences, 2023 - mdpi.com
Background: Neuro-immune pathways are engaged in antenatal and postpartum
depression. Aims: To determine if immune profiles influence the severity of prenatal …
depression. Aims: To determine if immune profiles influence the severity of prenatal …
[HTML][HTML] Inflammatory and neurodegenerative pathophysiology implicated in postpartum depression
RJ Worthen, E Beurel - Neurobiology of disease, 2022 - Elsevier
Postpartum depression (PPD) is the most common psychiatric complication associated with
pregnancy and childbirth with debilitating symptoms that negatively impact the quality of life …
pregnancy and childbirth with debilitating symptoms that negatively impact the quality of life …
The biological underpinnings of perinatal depressive symptoms: A multi-systems approach.
Background Well-established evidence exists of an association between depressive
symptoms and alterations in the stress and inflammatory response systems; however, the …
symptoms and alterations in the stress and inflammatory response systems; however, the …
Increased maternal inflammation and poorer infant neurobehavioural competencies in women with a history of major depressive disorder from the psychiatry research …
S Osborne, A Biaggi, K Hazelgrove, A Du Preez… - Brain, Behavior, and …, 2022 - Elsevier
Introduction Stress in pregnancy is associated with adverse outcomes in offspring, and
developmental programming is a potential mechanism. We have previously shown that …
developmental programming is a potential mechanism. We have previously shown that …
[HTML][HTML] Cytokines and tryptophan metabolites can predict depressive symptoms in pregnancy
Q Sha, Z Madaj, S Keaton, ML Escobar Galvis… - Translational …, 2022 - nature.com
Depression during and after pregnancy affects up to 20% of pregnant women, but the
biological underpinnings remain incompletely understood. As pregnancy progresses, the …
biological underpinnings remain incompletely understood. As pregnancy progresses, the …
Inflammation: a proposed intermediary between maternal stress and offspring neuropsychiatric risk
During pregnancy, programming of the fetal central nervous system establishes
vulnerabilities for emergence of neuropsychiatric phenotypes later in life. Psychosocial …
vulnerabilities for emergence of neuropsychiatric phenotypes later in life. Psychosocial …