Peptide dendrimer–doxorubicin conjugate‐based nanoparticles as an enzyme‐responsive drug delivery system for cancer therapy
C Zhang, D Pan, K Luo, W She, C Guo… - Advanced …, 2014 - Wiley Online Library
Peptide dendrimers have shown promise as an attractive platform for drug delivery. In this
study, mPEGylated peptide dendrimer–doxorubicin (dendrimer–DOX) conjugate‐based …
study, mPEGylated peptide dendrimer–doxorubicin (dendrimer–DOX) conjugate‐based …
Amphiphilic peptide dendritic copolymer-doxorubicin nanoscale conjugate self-assembled to enzyme-responsive anti-cancer agent
N Li, N Li, Q Yi, K Luo, C Guo, D Pan, Z Gu - Biomaterials, 2014 - Elsevier
Peptide dendrimer drug conjugate based nanoparticles are recently developed as a
potential candidate for drug delivery vehicle. In this study, we prepared and characterized …
potential candidate for drug delivery vehicle. In this study, we prepared and characterized …
The potential of self-assembled, pH-responsive nanoparticles of mPEGylated peptide dendron–doxorubicin conjugates for cancer therapy
W She, K Luo, C Zhang, G Wang, Y Geng, L Li, B He… - Biomaterials, 2013 - Elsevier
Nanoparticles, such as dendritic polymers, are currently investigated as excellent
candidates for drug delivery vehicles. In this study, we report the preparation and …
candidates for drug delivery vehicles. In this study, we report the preparation and …
Enzyme-responsive peptide dendrimer-gemcitabine conjugate as a controlled-release drug delivery vehicle with enhanced antitumor efficacy
C Zhang, D Pan, J Li, J Hu, A Bains, N Guys, H Zhu… - Acta biomaterialia, 2017 - Elsevier
Stimuli-responsive peptide dendrimer-drug conjugates have presented significant potential
for cancer therapy. To develop an effective nanoscale chemotherapeutic prodrug, we …
for cancer therapy. To develop an effective nanoscale chemotherapeutic prodrug, we …
Enzyme-responsive doxorubicin release from dendrimer nanoparticles for anticancer drug delivery
SJ Lee, YI Jeong, HK Park, DH Kang… - International journal …, 2015 - Taylor & Francis
Background Since cancer cells are normally over-expressed cathepsin B, we synthesized
dendrimer-methoxy poly (ethylene glycol)(MPEG)-doxorubicin (DOX) conjugates using a …
dendrimer-methoxy poly (ethylene glycol)(MPEG)-doxorubicin (DOX) conjugates using a …
Dendrimer–doxorubicin conjugate as enzyme-sensitive and polymeric nanoscale drug delivery vehicle for ovarian cancer therapy
C Zhang, D Pan, K Luo, N Li, C Guo, X Zheng… - Polymer Chemistry, 2014 - pubs.rsc.org
Peptide dendrimer-based nanoparticles have presented significant potential as candidates
for drug delivery system. In this study, we synthesized and characterized enzyme-responsive …
for drug delivery system. In this study, we synthesized and characterized enzyme-responsive …
Enzyme-sensitive cytotoxic peptide–dendrimer conjugates enhance cell apoptosis and deep tumor penetration
FH Liu, CY Hou, D Zhang, WJ Zhao, Y Cong… - Biomaterials …, 2018 - pubs.rsc.org
Peptide nanodrugs have been developed as promising antitumor chemotherapeutics
because they partially overcome the drawbacks of free peptide drugs, but insufficient tumor …
because they partially overcome the drawbacks of free peptide drugs, but insufficient tumor …
DOX-loaded peptide dendritic copolymer nanoparticles for combating multidrug resistance by regulating the lysosomal pathway of apoptosis in breast cancer cells
J Wang, N Li, L Cao, C Gao, Y Zhang… - Journal of Materials …, 2020 - pubs.rsc.org
Multidrug resistance (MDR) is a common phenomenon in clinical oncology and is a major
obstacle to cancer chemotherapy. Many nanoparticle (NP)-based drug delivery systems …
obstacle to cancer chemotherapy. Many nanoparticle (NP)-based drug delivery systems …
Co-delivery of cisplatin and doxorubicin by covalently conjugating with polyamidoamine dendrimer for enhanced synergistic cancer therapy
Because of the synergistic effects of drugs and minimal drug dose for cancer therapy,
combination chemotherapy is frequently used in the clinic. In this study, hyaluronic acid …
combination chemotherapy is frequently used in the clinic. In this study, hyaluronic acid …
RGD peptide-modified multifunctional dendrimer platform for drug encapsulation and targeted inhibition of cancer cells
Abstract Development of multifunctional nanoscale drug-delivery systems for targeted
cancer therapy still remains a great challenge. Here, we report the synthesis of cyclic …
cancer therapy still remains a great challenge. Here, we report the synthesis of cyclic …
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