Activated oncogenes have been detected in a variety of fresh solid tumours by transfection
on NIH3T3 cells (Bishop, 1987) and in most cases the transforming gene belongs to the …

We recently detected a novel activated oncogene by transfection analysis on NIH 3T3 cells
in five out of 20 primary human thyroid papillary carcinomas and in the available lymph node …

We have recently reported the activation of a new oncogene in human papillary thyroid
carcinomas. This oncogene, papillary thyroid carcinoma (PTC), is a novel rearranged …

Human thyroid epithelial (follicular) cells give rise to two malignant tumors—“follicular”
carcinomas, which metastasize almost exclusively via the bloodstream, and “papillary” …

We have recently reported that about 50% of papillary thyroid carcinomas harbor an
activated TRK or RET oncogene. Two retroviral vectors containing the activated TRK or …

In papillary thyroid carcinomas, we have identified two tumor-specific rearrangements of the
RET proto-oncogene leading to the formation of different transforming fusion products …

Using polymerase chain reaction amplification and oligonucleotide probing, the activation of
ras oncogenes in 24 benign and 20 malignant human thyroid neoplasms was examined …

The RET proto-oncogene encodes a transmembrane receptor of the tyrosine kinase family
and has frequently been found activated in human thyroid carcinomas of the papillary …

The ret oncogene frequently has been found activated in papillary thyroid carcinomas. A
previous characterization of ret activation revealed recombination of its tyrosine kinase …

We have investigated the PTC/retTPC oncogene, an activated form of ret proto-oncogene
with a specific rearrangement, in thyroid malignancies. Southern analysis was used to …