Oocyte quality is a well-established determinant of embryonic fate. However, the molecular
participants and biological markers that affect and may predict adequate embryonic …

Study question Is it possible to predict an euploid chromosomal constitution from RNA-Seq
data and identify a transcriptomic profile compatible with extended embryonic development …

Embryo development requires orchestrated events, finely regulated at the molecular and
cellular level by mechanisms which are progressively emerging from animal studies. With …

Simple Summary Despite the fact that human assisted reproduction has undergone
extensive development with positive effects on pregnancy, the rates of success are still low …

Various pathogenic factors can lead to oogenesis failure and seriously affect both female
reproductive health and fertility. Genetic factors play an important role in folliculogenesis and …

Successful human reproduction requires gamete maturation, fertilization, and early
embryonic development. Human oocyte maturation includes nuclear and cytoplasmic …

The success of implantation is an interactive process between the blastocyst and the uterus.
Synchronized development of embryos with uterine differentiation to a receptive state is …

Embryonic development is readily compromised by imperfections introduced during the
process of oocyte maturation. We discuss the nature and causes of these imperfections …

Epigenetic mechanisms such as DNA methylation regulate genomic imprinting and account
for the distinct non-equivalence of the parental genomes in the embryo. Chromosomal …

Mammalian oocytes and surrounding granulosa cells are metabolically coupled via gap
junctions. In growing follicles of the mouse, gap junctions between oocytes and granulosa …