Pemetrexed versus erlotinib in pretreated patients with advanced non–small cell lung cancer: a Hellenic Oncology Research Group (HORG) randomized phase 3 …

A Karampeazis, A Voutsina, J Souglakos… - Cancer, 2013 - Wiley Online Library
BACKGROUND In this superiority study, pemetrexed was compared with erlotinib in pre‐
treated patients with metastatic non–small cell lung cancer (NSCLC). METHODS Patients …

Pemetrexed (MTA) compared with erlotinib (ERL) in pretreated patients with advanced non-small cell lung cancer (NSCLC): Results of a randomized phase III …

L Vamvakas, S Agelaki, NK Kentepozidis… - Journal of Clinical …, 2010 - ascopubs.org
7519 Background: To compare the efficacy of MTA and ERL as second-line treatment of
patients with advanced/metastatic NSCLC. Methods: Pts were randomized either to MTA …

[HTML][HTML] A randomised phase II study of pemetrexed versus pemetrexed+ erlotinib as second-line treatment for locally advanced or metastatic non-squamous non …

C Dittrich, Z Papai-Szekely, N Vinolas… - European Journal of …, 2014 - Elsevier
Introduction Pemetrexed and erlotinib have been approved as second-line monotherapy for
locally advanced or metastatic non-small cell lung cancer (NSCLC). This multicentre …

[HTML][HTML] Three-arm randomised controlled phase 2 study comparing pemetrexed and erlotinib to either pemetrexed or erlotinib alone as second-line treatment for …

DH Lee, JS Lee, SW Kim, J Rodrigues-Pereira… - European journal of …, 2013 - Elsevier
Background This randomised controlled phase 2 study compared pemetrexed and erlotinib
in combination with either agent alone in terms of efficacy and safety as second-line …

[HTML][HTML] Erlotinib in combination with pemetrexed for patients with advanced non-small-cell lung cancer (NSCLC): a phase I dose-finding study

M Ranson, M Reck, A Anthoney, AR Hanauske… - Annals of oncology, 2010 - Elsevier
Background Erlotinib and pemetrexed are approved single agents for second-line treatment
of non-small-cell lung cancer (NSCLC) and, in combination, have shown synergistic …

Pemetrexed versus pemetrexed and carboplatin as second-line chemotherapy in advanced non–small-cell lung cancer: results of the GOIRC 02-2006 randomized …

A Ardizzoni, M Tiseo, L Boni, AD Vincent… - Journal of clinical …, 2012 - ascopubs.org
Purpose To compare efficacy of pemetrexed versus pemetrexed plus carboplatin in
pretreated patients with advanced non–small-cell lung cancer (NSCLC). Patients and …

Pemetrexed single agent in previously treated non-small cell lung cancer: a multi-institutional observational study

A Bearz, I Garassino, R Cavina, A Favaretto… - Lung cancer, 2008 - Elsevier
Several drugs have been approved for the treatment of patients affected by advanced non-
small cell lung cancer (NSCLC) in progression after first line chemotherapy: Docetaxel …

[PDF][PDF] Pemetrexed versus gefitinib versus erlotinib in previously treated patients with non-small cell lung cancer

J Hong, SY Kyung, SP Lee, JW Park… - The Korean journal …, 2010 - synapse.koreamed.org
Background/Aims: The efficacy and safety of pemetrexed, gefitinib, and erlotinib
administration in previously treated patients with non-small cell lung cancer (NSCLC) were …

Role of Pemetrexed in Sdvanced Non-Small-Cell Lung Cancer: Meta-Analysis of Randomized Controlled Trials, with Histology Subgroup Analysis

K Al-Saleh, C Quinton, PM Ellis - Current Oncology, 2012 - mdpi.com
Purpose: Platinum-based regimens represent the standard first-line treatment for non-small-
cell lung cancer (SNCLC). However, newer data have established a role for pemetrexed in …

[HTML][HTML] Efficacy differences of pemetrexed by histology in pretreated patients with stage IIIB/IV non-small cell lung cancer: review of results from an open-label …

K Kubota, S Niho, S Enatsu, Y Nambu… - Journal of Thoracic …, 2009 - Elsevier
Introduction Recent pivotal phase III studies in patients with advanced non-small cell lung
cancer (NSCLC) consistently showed greater survival benefit of pemetrexed in patients with …