Dynamic neuronal responses in cortical and thalamic areas during different phases of formalin test in rats
J Huang, JY Chang, DJ Woodward, LA Baccalá… - Experimental …, 2006 - Elsevier
Although formalin-induced activity in primary afferent fibers and spinal dorsal horn is well
described, the forebrain neural basis underlying each phase of behavior in formalin test has …
described, the forebrain neural basis underlying each phase of behavior in formalin test has …
Regional changes in forebrain activation during the early and late phase of formalin nociception: analysis using cerebral blood flow in the rat
TJ Morrow, PE Paulson, PJ Danneman, KL Casey - Pain, 1998 - Elsevier
This is the first neural imaging study to use regional cerebral blood flow (rCBF) in an animal
model to identify the patterns of forebrain nociceptive processing that occur during the early …
model to identify the patterns of forebrain nociceptive processing that occur during the early …
Second phase of formalin‐induced excitation of spinal dorsal horn neurons in spinalized rats is reversed by sciatic nerve block
GM Pitcher, JL Henry - European Journal of Neuroscience, 2002 - Wiley Online Library
Considerable debate persists concerning peripheral vs. central mechanisms underlying the
second phase of the nociceptive response in the formalin test in the rat. To gain insight into …
second phase of the nociceptive response in the formalin test in the rat. To gain insight into …
Electroencephalographic responses to the formalin test in rats
F Ichinose, M Miyazaki, T Goto, H Takahashi, K Terui… - Pain, 1999 - journals.lww.com
The formalin test is an animal model of persistent pain. Although biphasic behavioral
responses to formalin injection have been well described, the significance of the biphasic …
responses to formalin injection have been well described, the significance of the biphasic …
Formalin induces biphasic activity in C-fibers in the rat
WD McCall, KD Tanner, JD Levine - Neuroscience letters, 1996 - Elsevier
While the formalin test is a widely used behavioral model of tonic chemogenic pain, little is
known about the responses of primary afferent nociceptors to formalin. Formalin (2.5%, 50 …
known about the responses of primary afferent nociceptors to formalin. Formalin (2.5%, 50 …
Sex differences in the responses of spinal wide-dynamic range neurons to subcutaneous formalin and in the effects of different frequencies of conditioning electrical …
HJ You, DY Cao, B Yuan, L Arendt-Nielsen - Neuroscience, 2006 - Elsevier
The purpose of this study was to investigate sex-related differences in nociception elicited by
sc injection of different concentrations (1–5%) of formalin. Sc formalin-induced biphasic …
sc injection of different concentrations (1–5%) of formalin. Sc formalin-induced biphasic …
Functional activity mapping of the rat brainstem during formalin-induced noxious stimulation
CA Porro, M Cavazzuti, A Galetti, L Sassatelli - Neuroscience, 1991 - Elsevier
Functional activity changes in 35 selected structures of the rat brainstem elicited by
subcutaneous formalin injection in a forepaw were investigated by the [14 C] 2 …
subcutaneous formalin injection in a forepaw were investigated by the [14 C] 2 …
[HTML][HTML] Characterization of nociceptive behaviors induced by formalin in the glabrous and hairy skin of rats
E Erami, H Azhdari-Zarmehri, K Imoto… - Basic and clinical …, 2017 - ncbi.nlm.nih.gov
Methods: In this study, we compared nociceptive behaviors induced by formalin injections
(2%, 4%, and 8%) into either glabrous skin (plantar surface) of the hind paw or hairy skin of …
(2%, 4%, and 8%) into either glabrous skin (plantar surface) of the hind paw or hairy skin of …
Descending modulation of central neural plasticity in the formalin pain test
AL Vaccarino, DA Chorney - Brain research, 1994 - Elsevier
Subcutaneous injection of formalin produces a biphasic profile of pain response: a transient
early phase followed by a tonic late phase. A number of studies have indicated that the …
early phase followed by a tonic late phase. A number of studies have indicated that the …
Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin
KY Fu, AR Light, W Maixner - Neuroscience, 2000 - Elsevier
To determine whether initial nociceptive inputs caused by subcutaneous injection of formalin
into the hindpaw are necessary and/or sufficient for allodynic behavior and microglial …
into the hindpaw are necessary and/or sufficient for allodynic behavior and microglial …