Purpose: The present study was designed to investigate the role of myofibroblast
transdifferentiation and the conjunctival renin–angiotensin system (RAS) in the …

Chronic graft-versus-host disease (cGVHD) is a serious complication known to occur after
allogeneic hematopoietic stem cell transplantation. Clinical manifestation includes …

Purpose: To report the characteristics of the ocular surface in a previously established
sclerodermatous chronic graft-versus-host disease (cGVHD) mouse model. Methods: The …

Purpose: To evaluate whether fibrosis contributes to corneal transplant failure and to
determine whether effector CD4+ T cells, the key immune cells in corneal transplant …

Chronic graft-versus-host disease (cGVHD) of the ocular surface and lacrimal gland is a
vision-threatening condition that occurs after allogeneic bone marrow transplantation. In this …

Purpose: The present study was designed to investigate the role of ocular surface glycocalyx
and mucins in graft versus host disease (GVHD)-associated dry eye. The ameliorative effect …

Purpose: This study aimed to clarify the mechanisms and assess the characteristics of the
chronic graft-versus-host disease (cGVHD) fibrosis in the lacrimal gland (LG) of mice …

Graft-versus-host disease (GVHD) is a major complication after hematopoietic stem cell
transplantation (HSCT), and ocular GVHD can cause severe dry eye disease that can lead …

Activation of the immune system and progressive fibrosis are prominent features of chronic
graft-versus-host disease (cGVHD) after allogeneic hematopoietic stem cell transplantation …

purpose. Tissue atrophy and excessive fibrosis are prominent histologic features of chronic
graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation …