Achieving 2003 European lipid goals with rosuvastatin and comparator statins in 6743 patients in real-life clinical practice: DISCOVERY meta-analysis

A Middleton, AS Binbrek, FAH Fonseca… - … medical research and …, 2006 - Taylor & Francis
Background: There is an increasing body of evidence to support the benefits of reducing low-
density lipoprotein cholesterol (LDL-C) levels and this has been reflected in a lowering of …

Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center …

T Laks, E Keba, M Leiner, E Merilind… - Vascular Health and …, 2008 - Taylor & Francis
The aim of this multi-center, open-label, randomized, parallel-group trial was to compare the
efficacy of rosuvastatin with that of simvastatin in achieving the 1998 European …

Rosuvastatin is cost-effective compared with atorvastatin in reaching cholesterol goals

M Hirsch, J O'donnell, A Olsson - International journal of cardiology, 2005 - Elsevier
BACKGROUND: Lowering low-density lipoprotein cholesterol (LDL-C) levels reduces the
risk of coronary heart disease. The introduction of a highly efficacious new statin …

Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial

JM McKenney, PH Jones, MA Adamczyk… - … medical research and …, 2003 - Taylor & Francis
SUMMARY In the Statin Therapies for Elevated Lipid Levels compared Across doses to
Rosuvastatin (STELLAR) trial, the efficacy of rosuvastatin calcium (Crestor) was compared …

Rosuvastatin versus atorvastatin in achieving lipid goals in patients at high risk for cardiovascular disease in clinical practice: A randomized, open-label, parallel …

AS Binbrek, A Elis, M Al-Zaibag, J Eha, I Keber… - Current therapeutic …, 2006 - Elsevier
BACKGROUND:: The majority of clinical trials investigating the clinical benefits of lipid-
lowering therapies (LLTs) have focused on North American or western and nothern …

A randomised study comparing the efficacy and safety of rosuvastatin with atorvastatin for achieving lipid goals in clinical practice in Asian patients at high risk of …

J Zhu, B Tomlinson, YM Ro, KH Sim… - … medical research and …, 2007 - Taylor & Francis
Background: Most studies investigating the benefits of statins have focused on North
American and European populations. This study focuses on evaluating the lipid-lowering …

The DISCOVERY PENTA study: a DIrect Statin COmparison of LDL‐C Value–an Evaluation of Rosuvastatin therapY compared with atorvastatin

FAH Fonseca, A Ruiz, EG Cardona-Muñoz… - … medical research and …, 2005 - Taylor & Francis
Background: International guidelines emphasize the need to achieve recommended low-
density lipoprotein cholesterol (LDL‐C) levels in order to reduce morbidity and mortality …

Achieving lipid goals in real life: the Dutch DISCOVERY study

AFE Bots, JJP Kastelein… - … journal of clinical …, 2005 - Wiley Online Library
DISCOVERY Netherlands was an open‐label, randomised, multicentre study
(D3560/L00003) designed to compare the effects of rosuvastatin with those of atorvastatin …

Superior benefit of aggressive lipid-lowering therapy for high-risk patients using statins: the SUBARU study—more hypercholesterolemic patients achieve Japan …

M Kurabayashi, T Yamazaki… - … of atherosclerosis and …, 2008 - jstage.jst.go.jp
Aim: There have been few comparisons between rosuvastatin and other statins in Japanese
patients. This open-label, randomized, parallel-group comparative study was performed to …

LDL-C reductions and goal attainment among naive statin users in the Netherlands: real life results

EM Heintjes, MW Hirsch… - … medical research and …, 2008 - Taylor & Francis
Objective: The effectiveness of statin therapy in a real life setting may differ from that in
clinical trials, as physicians make non-randomised treatment decisions for patients with less …