Non-DSB clustered DNA lesions. Does theory colocalize with the experiment?
Z Nikitaki, V Nikolov, IV Mavragani, I Plante… - Radiation Physics and …, 2016 - Elsevier
Ionizing radiation results in various kinds of DNA lesions such as double strand breaks
(DSBs) and other non-DSB base lesions. These lesions may be formed in close proximity …
(DSBs) and other non-DSB base lesions. These lesions may be formed in close proximity …
Spectrum of complex DNA damages depends on the incident radiation
M Hada, BM Sutherland - Radiation research, 2006 - meridian.allenpress.com
Abstract Hada, M. and Sutherland, BM Spectrum of Complex DNA Damages Depends on
the Incident Radiation. Radiat. Res. 165, 223–230 (2006). Ionizing radiation induces …
the Incident Radiation. Radiat. Res. 165, 223–230 (2006). Ionizing radiation induces …
Clustered damages and total lesions induced in DNA by ionizing radiation: oxidized bases and strand breaks
BM Sutherland, PV Bennett, O Sidorkina, J Laval - Biochemistry, 2000 - ACS Publications
Ionizing radiation induces both isolated DNA lesions and clustered damages multiple
closely spaced lesions (strand breaks, oxidized purines, oxidized pyrimidines, or abasic …
closely spaced lesions (strand breaks, oxidized purines, oxidized pyrimidines, or abasic …
Repair of DNA damage induced by accelerated heavy ions—a mini review
R Okayasu - International journal of cancer, 2012 - Wiley Online Library
Increasing use of heavy ions for cancer therapy and concerns from exposure to heavy
charged particles in space necessitate the study of the basic biological mechanisms …
charged particles in space necessitate the study of the basic biological mechanisms …
Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy
B Jakob, JH Rudolph, N Gueven… - Radiation …, 2005 - meridian.allenpress.com
Abstract Jakob, B., Rudolph, JH, Gueven, N., Lavin, MF and Taucher-Scholz, G. Live Cell
Imaging of Heavy-Ion-Induced Radiation Responses by Beamline Microscopy. Radiat. Res …
Imaging of Heavy-Ion-Induced Radiation Responses by Beamline Microscopy. Radiat. Res …
Investigation of neutron-induced damage in DNA by atomic force microscopy: experimental evidence of clustered DNA lesions
D Pang, BL Berman, S Chasovskikh… - Radiation …, 1998 - meridian.allenpress.com
Using atomic force microscopy (AFM), we have investigated neutron-induced DNA double-
strand breaks in plasmids in aqueous solution. AFM permits direct measurement of …
strand breaks in plasmids in aqueous solution. AFM permits direct measurement of …
Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break
K Datta, P Jaruga, M Dizdaroglu… - Radiation …, 2006 - meridian.allenpress.com
Abstract Datta, K., Jaruga, P., Dizdaroglu, M., Neumann, RD and Winters, TA Molecular
Analysis of Base Damage Clustering Associated with a Site-Specific Radiation-Induced …
Analysis of Base Damage Clustering Associated with a Site-Specific Radiation-Induced …
[HTML][HTML] Clustered DNA double-strand breaks: biological effects and relevance to cancer radiotherapy
JA Nickoloff, N Sharma, L Taylor - Genes, 2020 - mdpi.com
Cells manage to survive, thrive, and divide with high accuracy despite the constant threat of
DNA damage. Cells have evolved with several systems that efficiently repair spontaneous …
DNA damage. Cells have evolved with several systems that efficiently repair spontaneous …
[HTML][HTML] 3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle …
Y Hagiwara, A Niimi, M Isono, M Yamauchi… - Oncotarget, 2017 - ncbi.nlm.nih.gov
DNA double-strand breaks (DSBs) induced by ionising radiation are considered the major
cause of genotoxic mutations and cell death. While DSBs are dispersed throughout …
cause of genotoxic mutations and cell death. While DSBs are dispersed throughout …
Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation
A Asaithamby, DJ Chen - Mutation Research/Fundamental and Molecular …, 2011 - Elsevier
Low-linear energy transfer (LET) radiation (ie, γ-and X-rays) induces DNA double-strand
breaks (DSBs) that are rapidly repaired (rejoined). In contrast, DNA damage induced by the …
breaks (DSBs) that are rapidly repaired (rejoined). In contrast, DNA damage induced by the …