Ionizing radiation results in various kinds of DNA lesions such as double strand breaks
(DSBs) and other non-DSB base lesions. These lesions may be formed in close proximity …

Abstract Hada, M. and Sutherland, BM Spectrum of Complex DNA Damages Depends on
the Incident Radiation. Radiat. Res. 165, 223–230 (2006). Ionizing radiation induces …

Ionizing radiation induces both isolated DNA lesions and clustered damages multiple
closely spaced lesions (strand breaks, oxidized purines, oxidized pyrimidines, or abasic …

Increasing use of heavy ions for cancer therapy and concerns from exposure to heavy
charged particles in space necessitate the study of the basic biological mechanisms …

Abstract Jakob, B., Rudolph, JH, Gueven, N., Lavin, MF and Taucher-Scholz, G. Live Cell
Imaging of Heavy-Ion-Induced Radiation Responses by Beamline Microscopy. Radiat. Res …

Using atomic force microscopy (AFM), we have investigated neutron-induced DNA double-
strand breaks in plasmids in aqueous solution. AFM permits direct measurement of …

Abstract Datta, K., Jaruga, P., Dizdaroglu, M., Neumann, RD and Winters, TA Molecular
Analysis of Base Damage Clustering Associated with a Site-Specific Radiation-Induced …

Cells manage to survive, thrive, and divide with high accuracy despite the constant threat of
DNA damage. Cells have evolved with several systems that efficiently repair spontaneous …

DNA double-strand breaks (DSBs) induced by ionising radiation are considered the major
cause of genotoxic mutations and cell death. While DSBs are dispersed throughout …

Low-linear energy transfer (LET) radiation (ie, γ-and X-rays) induces DNA double-strand
breaks (DSBs) that are rapidly repaired (rejoined). In contrast, DNA damage induced by the …