Trauma remains the leading cause of death and disability in adults and is responsible for
more life lost and, more importantly, quality life lost than heart disease, human …

Acute traumatic coagulopathy (ATC) is the failure of coagulation homeostasis that can
rapidly arise following traumatic injury, hemorrhage, and shock; it is associated with higher …

Hemorrhage is the most important contributing factor of acute-phase mortality in trauma
patients. Previously, traumatologists and investigators identified iatrogenic and resuscitation …

Recent observational studies have identified an acute coagulopathy in trauma victims that is
present on arrival in the emergency room. It has been associated with a four-fold increase in …

Trauma remains the leading cause of death with bleeding as the primary cause of
preventable mortality during the first 24 h following trauma. When death occurs, it happens …

Trauma is a leading cause of death and disability. Hemorrhage is the major mechanism
responsible for death during the first 24 hours following trauma. One quarter of severely …

Traumatic injury is one of the leading causes of death, with uncontrolled hemorrhage from
coagulation dysfunction as one of the main potentially preventable causes of the mortality …

Coagulopathy after traumatic injury has multiple etiologies. It may result from overwhelming
activation of tissue factor, consumption of circulating coagulation proteins, massive …

Introduction: Injury is the second leading cause of death worldwide, and as much as 40% of
injury-related mortality is attributed to uncontrollable hemorrhage. This persists despite …

Background: Recent civilian studies have documented a relationship between increased
mortality and the presence of an early coagulopathy of trauma diagnosed in the emergency …